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Relationship Between Proprioceptive Flexibility and the Occurrence of Lower Limb Ligament Injury in Pivot-contact Sports

Relationship Between Proprioceptive Flexibility and the Occurrence of Lower Limb Ligament Injury in Pivot-contact Sports

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07028723
Acronym
FlexiPro
Enrollment
150
Registered
2025-06-19
Start date
2025-06-30
Completion date
2028-01-01
Last updated
2025-07-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower Limb Ligament Injury

Keywords

Anterior Cruciate Ligament (ACL), Laterale Ankle Sprain (LAS), Inferior Tibio-fibular syndesmosis, Proprioception, Postural control, Injury Prevention

Brief summary

Among young athletes involved in pivot and pivot-contact sports (soccer, handball, rugby, etc.), lateral ankle sprains and lesions of the anterior cruciate ligament (ACL) are the most frequent ligament injuries. Despite existing prevention programs, these injuries lead to prolonged downtime, risk of recurrence and long-term sequelae. A little-studied risk factor is proprioceptive rigidity, defined as the central nervous system's difficulty in adapting the use of sensory information (proprioception) according to environment and motor context. This deficit could limit the ability to maintain balance in high-risk situations, thereby increasing the likelihood of injury. To our knowledge, there is no evidence of a direct link between proprioceptive profile (flexible/rigid) and the incidence of lower-limb ligament injury. If such a link is established, preventive strategies focusing on the recovery of an optimal proprioceptive profile could be developed in an attempt to limit the occurrence of ligament injuries in young elite and sub-elite athletes, and thus limit the medical, financial and personal repercussions for these athletes.

Interventions

OTHERproprioceptive profile measurement

Proprioceptive profile is measured by assessing static bipodal balance on a force platform. The patient is asked to stand motionless in bipodal support on a stable and then unstable floor, with vision masked by an eye mask. The investigators randomly apply a tendon vibration (80Hz) to the subjects' Achilles tendons or paravertebral muscles. This vibration alters proprioceptive information in the vibrated zone, leading to a disturbance in postural balance and an increased displacement of the center of pressure, whose position is continuously calculated from the force platform's sensors. Thus, depending on the amount of displacement of the center of pressure, the investigator calculates a proprioceptive weighting ratio (PWR) to deduce the weight assigned by the Central Nervous System to the various proprioceptive inputs during the postural task. An PWR of 1 indicates 100% use of information from the ankle, while an PWR of 0 means 100% use of information from the hip.

Sponsors

University Hospital, Montpellier
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
14 Years to 25 Years
Healthy volunteers
Yes

Inclusion criteria

* Athlete practicing in a high-level program * Aged between 14 and 25 * Practicing a pivot-contact sport (rugby, soccer, handball)

Exclusion criteria

* Lower limb injury \<6 weeks prior to inclusion * Concussion \<6 weeks prior to inclusion * Known neurological or vestibular disorder * Lack of consent from athlete or legal guardians * Non-affiliation with a social security scheme * Persons under court protection * Participant in another study with an ongoing exclusion period

Design outcomes

Primary

MeasureTime frameDescription
Rate of occurrence of lower limb ligament injuries in groups of athletes with rigid proprioceptive profilesDuring 1 year after inclusionData collection on the occurrence of injuries will be carried out by club doctors, who will complete a questionnaire sent to them by e-mail by the investigator. They will then be contacted once a month by a single person to centralize the data.
Rate of occurrence of lower limb ligament injuries in groups of athletes with flexible proprioceptive profilesDuring 1 year after inclusionData collection on the occurrence of injuries will be carried out by club doctors, who will complete a questionnaire sent to them by e-mail by the investigator. They will then be contacted once a month by a single person to centralize the data.

Secondary

MeasureTime frameDescription
Describe the relationship between proprioceptive stiffness and the period of the seasonDuring 1 year after inclusionPeriod of season (1st, 2nd, 3rd or 4th quarter of season)
Describe the relationship between proprioceptive stiffness and exposure time during training and matchesDuring 1 year after inclusionNumber of hours of practice (training and match)
Describe the relationship between proprioceptive stiffness and injury mechanism (contact/non-contact)During 1 year after inclusionDirect (contact) or indirect (non-contact) injury mechanism
Describe the prevalence of rigid and flexible profiles in this population and according to the sport played (rugby, soccer, handball).During 1 year after inclusion
Describe the relationship between proprioceptive stiffness and occurrence of a first or recurrent injuryDuring 1 year after inclusionFirst episode or recurrence
Describe the relationship between proprioceptive stiffness and time to return to sport at the same levelDuring 1 year after inclusionTime to return to sport at same level
Describe the relationship between proprioceptive stiffness and action during which injury occurs (attack/defense)During 1 year after inclusionAction of injury (attack or defense)
Describe the relationship between proprioceptive stiffness and the period of training or match during which the injury occurred (training or match divided into 4)During 1 year after inclusionPeriod of injury (1st, 2nd, 3rd or 4th quarter of training/match)

Countries

France

Contacts

Primary ContactBenoit ATTALIN, MD
fed-medecinedusport@chu-montpellier.fr+33467330565

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026