Respiratory Function and Oxygenation in Smokers and Non-smokers

A Comparison of Respiratory Function, Exercise Capacity and Oxygenation Between Smokers and Non-smokers

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07027956

Enrollment

Registered

2025-06-19

Start date

2025-05-28

Completion date

2025-12-31

Last updated

2025-06-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Smoking, Tobacco

Brief summary

This study aimed to compare respiratory function, exercise capacity, and intercostal muscle oxygenation in healthy smokers and non-smokers.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

(Smokers): * According to the World Health Organization and ICD smoking addiction criteria, consuming at least one cigarette every day for the last year * Volunteering to participate in research * Able to walk and cooperate

Exclusion criteria

(Smokers): * Having any cardiopulmonary disease * Having a musculoskeletal problem that could affect the tests * Failure to comply with tests Inclusion Criteria (Non-smokers): * According to the World Health Organization and ICD smoking addiction criteria, having never smoked or not having smoked in the last year * Volunteering to participate in research * Able to walk and cooperate

Design outcomes

Primary

Measure	Time frame	Description
Peak expiratory flow	1st day	Peak expiratory flow (PEF) will be assessed using spirometry.
Forced mid-expiratory flow	1st day	Forced mid-expiratory flow (FEF25-75) will be assessed using spirometry.
Inspiratory muscle strength	1st day	Strength index will be evaluated.
Forced vital capacity	1st day	Forced vital capacity (FVC) will be assessed using spirometry.
Forced expiratory volume in one second	1st day	Forced expiratory volume in one second (FEV1) will be assessed using spirometry
Forced expiratory volume in one second/forced vital capacity ratio	1st day	Forced expiratory volume in one second/forced vital capacity ratio will be assessed using spirometry.
Exercise capacity	2nd day	will be evaluated with 6 minute walk test and total distance will be recorded.
Intercostal muscle oxygenation	2nd day	During the 6-minute walking test, oxygenation of the intercostal muscles will be evaluated with a monitor.

Countries

Turkey (Türkiye)

Contacts

Primary ContactMerve Firat

mervefirat@ahievran.edu.tr+90 850 441 02 44

Outcome results