Antimalarials, Artemisinins, Drug Therapy, Combination, Hospitalization, Malaria, Falciparum, Plasmodium Falciparum, Retrospective Studies, Treatment Outcome
Conditions
Brief summary
This study looks at how doctors in three hospitals in France treat patients with a serious form of malaria caused by Plasmodium falciparum. It focuses on cases where the level of malaria parasites in the blood is 4% or higher. The study will compare how often a type of medicine called ACT (artemisinin-based combination therapy) is used on its own instead of the usual first-choice treatment (intravenous artesunate), and whether ACT works just as well. It will also check how well patients recover, whether they have complications, and how long they stay in the hospital.
Interventions
None listed
Sponsors
Centre Hospitalier de Saint-Denis
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Adult patients aged 18 years or older. * Diagnosis of Plasmodium falciparum malaria with a parasitemia level ≥ 4%.
Exclusion criteria
\- Patients under 18 years old
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients treated with artemisinin-based combination therapy (ACT) alone for Plasmodium falciparum malaria with parasitemia ≥4%. | 1 month |
Countries
France
Outcome results
None listed