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Neural Mobilization Exercises on Pain and Central Sensitization

The Effect of Neural Mobilization Exercises on Pain and Central Sensitization in Individuals With Lateral Epicondylitis: A Randomized Controlled Trial

Status
Suspended
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07027059
Enrollment
30
Registered
2025-06-18
Start date
2026-02-01
Completion date
2027-03-01
Last updated
2026-02-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lateral Epicondylitis

Keywords

lateral Epicondylitis

Brief summary

This study aims to investigate the effects of neural mobilization exercises on central sensitization and pain characteristics in individuals with lateral epicondylitis. Enrolled participants will be randomly assigned to two groups. One group will receive routine exercises and ESWT treatment, while the other group will receive neural mobilization exercises in addition to routine exercises and ESWT treatment.

Detailed description

This study aims to investigate the effects of neural mobilization exercises on central sensitization and pain characteristics in individuals with lateral epicondylitis. Enrolled participants will be randomly assigned to two groups. One group will receive routine exercises and ESWT treatment, while the other group will receive neural mobilization exercises in addition to routine exercises and ESWT treatment. Median nerve mobilizations will be implemented as the neural mobilization exercises. All groups will receive two sessions per week and complete the process in four weeks; therefore, they will have received a total of eight sessions by the end of the study. Routine exercises and median nerve mobilizations will be implemented in every session (twice a week), while ESWT will be implemented once a week. Median nerve mobilizations will be administered in 5 sets, each consisting of 10 repetitions per session. Before and after the sessions, subjective factors related to pain will be assessed using the Central Sensitization Scale and the Pain Catastrophizing Scale, as well as pressure pain threshold measurements.

Interventions

An exercise to increase median nerve mobility by flexing and extending fingers, wrist, elbow, shoulder, and neck

BEHAVIORALroutine exercises for lateral epicondylisits

eccentric strengthening exercises

Sponsors

Izmir Katip Celebi University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Clinical diagnosis of lateral epicondylitis * 18-65 years old

Exclusion criteria

Any other pathology, disease, condition, pain, surgery on the elbow, wrist, fingers, shoulder, or neck in the last year

Design outcomes

Primary

MeasureTime frameDescription
Central Sensitizationbaseline and after the 8 sessions (4th week)pressure pain threshold

Secondary

MeasureTime frameDescription
Central Sensitizationbaseline and after the 8 sessions (4th week)Central Sensitization scale
Pain Catastrophizingbaseline and after the 8 sessions (4th week)Pain Catastrophizing scale

Countries

Turkey (Türkiye)

Contacts

PRINCIPAL_INVESTIGATORkevser sevik kacmaz, pt, phd

Izmir Katip Celebi University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 24, 2026