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Comparative Analysis of RIRS Scoring System and Resorlu Unsal Stone Score (RUSS) for Predicting Stone-free Rate After Retrograde Intrarenal Surgery

Comparative Analysis of RIRS Scoring System and Resorlu Unsal Stone Score (RUSS) for Predicting Stone-Free Rate After Retrograde Intrarenal Surgery: A Prospective Cohort Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07026721
Enrollment
60
Registered
2025-06-18
Start date
2024-01-01
Completion date
2024-12-29
Last updated
2025-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Stones

Brief summary

Several studies have investigated the use of scoring systems for predicting stone-free rates after RIRS. Previous research has evaluated the RIRS Scoring System, RUSS, and other similar systems in different patient populations. This study was conducted to compare RIRS scoring system and Resorlu Unsal Stone Score (RUSS) for predicting stone free rate.

Interventions

The intervention involves Retrograde Intrarenal Surgery (RIRS) performed using a flexible ureteroscope to access the renal collecting system via a retrograde (urethra → bladder → ureter → kidney) approach. Stones are fragmented using a holmium:YAG laser, with or without the use of a ureteral access sheath, depending on the case. What distinguishes this intervention from others is the integration of preoperative scoring systems-specifically the RIRS Scoring System and the Resorlu Unsal Stone Score (RUSS)-to predict stone-free outcomes and guide case selection and surgical planning. Additionally, all procedures are performed by experienced endourologists following a standardized protocol, including consistent patient positioning, anesthesia, access technique, and post-operative imaging at defined intervals to assess outcomes.

Sponsors

Maharajgunj Medical Campus
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patients more than 18 years of age undergoing RIRS for renal stone * providing informed written consent

Exclusion criteria

* Previous renal and ureteric surgeries * coexisting bladder, ureteral stone

Design outcomes

Primary

MeasureTime frame
Correlation between the RIRS Scoring System and stone-free rate after Retrograde Intrarenal Surgery (RIRS), assessed using CT KUB12 months
Correlation between the Resorlu-Unsal Stone Score (RUSS) and stone-free rate after Retrograde Intrarenal Surgery (RIRS), assessed using CT KUB12 months

Secondary

MeasureTime frameDescription
Stone Burden as a Predictor of Stone-Free Rate After RIRSPreoperative assessment and 1 month postoperatively for stone-free statusCorrelation between stone burden (mm²) and stone-free rate after Retrograde Intrarenal Surgery (RIRS
Stone Density as a Predictor of Stone-Free Rate After RIRSPreoperative assessment and 1 month postoperatively for stone-free statusCorrelation between stone density (Hounsfield Units, HU) and stone-free rate after RIRS

Countries

Nepal

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026