Comparison of Two Different Methods for Calculating Intraocular Lens Tilt and Decentration

Agreement and Reproducibility of Intraocular Lens Tilt and Decentration Measurements: A Comparison Between CASIA2 and CILT

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07025707

Enrollment

Registered

2025-06-17

Start date

2025-07-01

Completion date

2025-09-01

Last updated

2025-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraocular Lens

Brief summary

Agreement and Reproducibility of Intraocular Lens Tilt and Decentration Measurements: A Comparison between CASIA2 and CILT

Detailed description

This prospective observational study evaluates the agreement and reproducibility of intraocular lens (IOL) tilt and decentration measurements obtained from two different imaging modalities: the CASIA2 anterior segment swept-source optical coherence tomography (AS-SS-OCT) system and the Calculator for Intraocular Lens Tilt (CILT) software, based on standardized anterior segment image analysis.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

21 Years to No maximum

Inclusion criteria

* planned cataract surgery * agreement to participation

Exclusion criteria

* Zonulolysis * Strabismus * Reduced Compliance * Axial length \<20 or \>25 mm * Keratokonus * PEX

Design outcomes

Primary

Measure	Time frame	Description
Intraocular Lens Tilt (CASIA2 and CILT)	Measured during the pre-surgery examination under normal pupil conditions and after pharmacologic dilation (45 minutes post-mydriatic instillation).	Intraocular lens (IOL) tilt, measured in degrees, assessed from anterior segment swept-source optical coherence tomography (AS-SS-OCT) images using the CASIA2 system and CILT software. Tilt is defined as the angle between the IOL plane and the corneal vertex.
Intraocular Decentration (CASIA2 and CILT)	Measured during the pre-surgery examination under normal pupil conditions and after pharmacologic dilation (45 minutes post-mydriatic instillation).	Intraocular lens (IOL) decentration, measured in micrometers, assessed from anterior segment swept-source optical coherence tomography (AS-SS-OCT) images using the CASIA2 system and CILT software. Decentration is defined as the distance between the IOL center and the corneal vertex.

Countries

Austria

Contacts

Primary ContactKonstantin Seiller-Tarbuk, Dr. med.

konstantin.seiller@gmail.com00431211215141

Outcome results