Critical Illness, Energy Requirement, Equation, Indirect Calorimetry, Malnutrition
Conditions
Brief summary
The goal of this observational study is to compare energy requirements estimated by predictive equation and indirect calorimetry across different BMI categories, and to examine how these estimates, along with early nutritional strategies and progressive caloric delivery relate to ICU outcomes. The main questions it aims to answer are: 1. To evaluate whether predictive equation and/or indirect calorimetry provides accurate caloric targets in critically ill patients. 2. To identify high-risk malnutrition patients (underweight, normal and overweight, obese) who may benefit most from IC-based measurement. 3. To investigate the impact of caloric strategies and nutritional achievement during the acute phase on the length of ICU stay.
Interventions
OTHERTotal energy requirement calculated by predictive equation
Critically ill patients are highly susceptible to malnutrition, making accurate caloric estimation essential to prevent both underfeeding and overfeeding during the acute phase in the ICU. Although predictive equations (PE) are widely used to estimate energy requirement, indirect calorimetry (IC) remains the gold standard. This study aimed to compare energy requirements estimated by PE and IC across different BMI categories.
Sponsors
Taipei Medical University Shuang Ho Hospital
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 105 Years
Healthy volunteers
No
Inclusion criteria
* Length of ICU stay \> 4 days * Mechanically ventilated adults (\>20 y/o) * Tube feeding * At high risk of malnutrition by Global Leadership Initiative on Malnutrition (GLIM) criteria: underweight and obesity * Doctor's preference: cachexia, hypermetabolic status, TPN etc.,…
Exclusion criteria
* Length of ICU stay \<4 days * Mechanically ventilated adults (\<=20 y/o)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The primary outcome was ICU length of stay. | From admitted to ICU which defined as day 1, until transferred to the general wards or expired, up to 12 weeks. | This study aimed to compare energy requirements estimated by PE and IC across different BMI categories, and to examine how these estimates, along with early nutritional strategies and progressive caloric delivery relate to the length of ICU stay. |
Countries
Taiwan
Outcome results
None listed