Influence of Hospital Volume on Mortality and Short-term Postoperative Outcomes in Uncomplex General Surgery in Switzerland

Influence of Hospital Volume on Mortality and Short-term Postoperative Outcomes in Uncomplex General Surgery in Switzerland: A Retrospective National Registry Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07022665

Enrollment

399701

Registered

2025-06-15

Start date

2013-01-01

Completion date

2023-03-01

Last updated

2025-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystolithiasis, Cholecystitis, Inguinal Hernia, Femoral Hernia, Umbilical Hernia, Appendicitis

Brief summary

The effect of centralisation measures on the operative outcomes after any type of surgery in Switzerland has not been highlighted yet. This study aims to investigate the influence of the annual case-specific hospital volume on uncomplex general surgery. The four operations investigated are appendectomy, cholecystectomy, umbilical hernia repair, and inguinal/femoral hernia repair.

Interventions

PROCEDUREAppendicectomy

Appendicectomy for appendicitis

PROCEDURECholecystectomy

Cholecystectomy for cholecystolithiasis and/or cholecystitis

PROCEDUREUmbilical hernia repair

Any kind of umbilical hernia repair

PROCEDUREInguinal and/or femoral hernia repair

Any kind of inguinal and/or femoral hernia repair

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Inclusion criteria

* All patients with appendicectomy for appendicitis, cholecystectomy for cholecystolithiasis and/or cholecystitis , umbilical hernia repair, or inguinal and/or femoral hernia repair

Exclusion criteria

* incomplete case documentation * age under 20 years * other hospitals than general or surgical hospitals * no index operation

Design outcomes

Primary

Measure	Time frame	Description
Mortality	Periprocedural	The association between the hospital volume and the postoperative mortality Mortality Yes or No Hospital volume as marginal effect Association with GAM logistic regression

Secondary

Measure	Time frame	Description
Reoperation	Periprocedural	The association between the hospital volume and the reoperation rate Reoperation Yes or No Hospital volume as marginal effect Association with GAM logistic regression
Length of hospital stay	Periprocedural	The association between the hospital volume and the length of hospital stay Length of hospital stay in days Hospital volume as marginal effect Association with quantile regression
Sociodemographic trends	2013 - 2022	—

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026