Shock, Critical Illness
Conditions
Keywords
Cheeta NICOM, Bioreactance, Transthoracic Echocardiography, Passive Leg Raising, Stroke Volume, Shock Assssment, Noninvasive Cardiac Output Monitoring
Brief summary
This study aims to evaluate the correlation between stroke volume measurements obtained by transthoracic echocardiography and bioreactance-based noninvasive cardiac output monitoring. The primary objective is to assess the level of agreement between these two modalities in critically ill patients.
Detailed description
In this prospective observational study, patients presenting with clinical signs of shock will be enrolled after obtaining informed consent. Stroke volume (SV) will be measured using both transthoracic echocardiography and bioreactance-based noninvasive cardiac output monitoring (Cheetah NICOM). SV will be recorded before and after passive leg raising (PLR) to evaluate the correlation between the two methods in terms of absolute values and directional changes (increase or decrease). No therapeutic intervention will be performed as part of the study; all clinical decisions will remain under the discretion of the treating medical team.
Interventions
DEVICECheetah NICOM
Bioreactance-based noninvasive cardiac output monitoring device used to measure stroke volume before and after passive leg raising. Used solely for observational measurement. No therapeutic intervention is performed.
Sponsors
University of Nevada, Las Vegas
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Age ≥ 18 years * Clinical diagnosis of shock as determined by the treating ICU physician (e.g., hypotension requiring vasopressors or evidence of end-organ hypoperfusion) * Able to obtain informed consent from the patient or a legally authorized representative * Enrollment within 24 hours of ICU admission
Exclusion criteria
* Pregnancy * Known severe aortic valve disease or dynamic left ventricular outflow tract obstruction * Morbid obesity (BMI \> 40) that precludes accurate echocardiographic imaging Presence of cardiac arrhythmias (e.g., atrial fibrillation with rapid ventricular response) affecting stroke volume measurements * Implanted cardiac assist devices (e.g., LVAD, pacemaker dependency) * Imminent death or decision for comfort care only
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Correlation Between Stroke Volume Measurements by Echocardiography and Bioreactance Monitoring | Within 1 hour of enrollment | Pearson correlation coefficient between stroke volume measurements obtained using transthoracic echocardiography and those obtained using bioreactance-based monitoring (Cheetah NICOM) in response to passive leg raising. |
Countries
United States
Contacts
Primary ContactMutsumi J Kioka, Medical Doctor
Backup ContactOffice of Research Integrity Human Subjects UNLV
Outcome results
None listed