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Comparison of Efficacy of Topical Adaplene Gel Versus Crythotherapy in Recurrent Plantar Warts

Comparison of Efficacy of Topical Adapalene Gel Versus Cryotherapy in Recurrent Plantar Warts

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07016360
Enrollment
98
Registered
2025-06-11
Start date
2025-09-15
Completion date
2026-09-15
Last updated
2026-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Viral Warts

Keywords

Plantar warts, Topical adapalene gel, Cryotherapy

Brief summary

This is a comparative study between two treatment options for skin viral infection.

Detailed description

This is a comparative study between two treatment for viral infection in epidermal layer of skin that proliferates slowly forming thick, growths. This study will compare and evaluate the differences in efficacy between topical liquid nitrogen and topical retinoids.

Interventions

Topical adapalene is a retinoid that helps in epidermal changes. Cryotherapy is a liquid nitrogen applied to affected parts for 6 months

PROCEDURETopical Liquid Nitrogen application

Liquid Nitrogen will be applied to affected parts.

Sponsors

Khyber Teaching Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

\- Patients age limit 18-60 Years Patients with either gender (Male/Female) Patients with recurrent plantar warts

Exclusion criteria

* Pregnancy/lactation. Pt on topical or systemic therapy in last 6 months. On immunosuppressants. \> 5 lesions. Pts with local secondary infections.

Design outcomes

Primary

MeasureTime frameDescription
Efficacy of Treatment06 monthsIt will be defined through visual inspection by observing the complete clearance of the warts after 8 weeks administration of the treatment in both groups

Countries

Pakistan

Contacts

CONTACTSaba Naz, MBBS
sabikhattak477@gmail.com+923209600115
PRINCIPAL_INVESTIGATORSaba Naz, MBBS

Khyber Teaching Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 30, 2026