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PAPE Effect With Blood Flow Restriction and Push-Up Exercise (Post-Activation Performance Enhancement)

Acute Effects of Push-Up Exercise Performed Under Varying Blood Flow Restriction Conditions on Upper Extremity Explosive Power Performance

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07015515
Acronym
PAPE
Enrollment
30
Registered
2025-06-11
Start date
2025-06-20
Completion date
2025-08-20
Last updated
2025-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Flow Restriction Exercise

Keywords

BFR, push-up exercise, PAPE, radar measurement, explosive power

Brief summary

This study aims to compare the acute effects of push-up exercises performed under different blood flow restriction (BFR) conditions on upper extremity explosive strength performance, measured via the seated unilateral medicine ball throw test.

Detailed description

The study includes three push-up conditions (BFR, sham BFR, and no BFR). Performance is evaluated via medicine ball throws at the 4th, 8th, and 12th minutes post-exercise. Exercises are applied in a crossover design with 50% limb occlusion pressure (LOP) BFR, sham, and control arms. Throw distance and ball velocity (measured by radar device) are primary outcomes. RPE scale is used to assess perceived exertion.

Interventions

OTHERSham blood flow restriction exercise

a BFR cuff will be placed on the upper extremity in the same location as in the real BFR group. During the application, the participant will be led to believe that the cuff is being inflated, although no actual pressure will be applied. The participant will see the cuff being wrapped and apparently inflated, but there will be no physical pressure restricting circulation during the exercise. This aims to control the psychological effects (e.g., the belief that something is being applied) on performance

OTHERControl group

Participants perform push-up exercises without any cuff application. The same repetition and rest protocol is followed

OTHERBlood flow restriction exercise group

Participants will perform push-up exercises with 50% arterial occlusion pressure applied to their dominant arm. The cuff is inflated before the exercise and maintained throughout 3 sets of 5 repetitions. There is a 2-minute rest between sets.

Sponsors

Istanbul University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 25 Years
Healthy volunteers
Yes

Inclusion criteria

* Being between 18 and 25 years old * Being a volleyball player * Having trained regularly in the last 6 months * Ability to perform at least 5 repetitions of push-up with own body weight * Voluntarily agreeing to participate and signing the informed consent form

Exclusion criteria

* History of shoulder or upper extremity injury requiring physical therapy or surgery * History of venous thromboembolism * Hematological disorders * Coronary artery disease * Peripheral arterial disease * Hypertension (systolic/diastolic \> 140 mmHg/90 mmHg) * History or high risk of deep vein thrombosis * Blood clotting disorders * Poor circulation * Inadequate lymphatic system * History of endothelial dysfunction * Varicose veins * Peripheral vascular disease * Diabetes * Easy bruising * Active infection * Cancer * Renal failure * Pregnancy * Intolerance to intervention

Design outcomes

Primary

MeasureTime frameDescription
throw distancewill be measured immediately after the exercise protocol is completed three times at 4th, 8th, and 12th minutesSeated unilateral medicine ball throw distance (in cm) -

Secondary

MeasureTime frameDescription
Ball velocity (km/h)will be measured by radar device after completion of the exercise three times at 4th, 8th, and 12th minutesspeed at which a ball travels immediately after being thrown
Rating of Perceived Exertion (RPE)1 day (will be assessed at the end of the push-up exercise)will be assessed via Borg Rating of Perceived Exertion Scale (6-20). Borg scale is used o quantify an individual's subjective perception of exercise intensity. It provides a numerical scale, typically ranging from 6 to 20. Higher scores on the scale indicate a greater subjective sense of difficulty or effort perceived by the individual.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026