Intractable Epilepsy
Conditions
Brief summary
The goal of this project is to study how the brain reacts to a small electrical signal. Researchers will be using a novel combination of recording electrodes. The researchers will measure the brain response from these electrodes.
Interventions
DEVICEstimulating probes and electrodes
Subdural electrodes and/or ball tip probes will be used intraoperatively to provide electrical stimulation to the brain.
Sponsors
University of Michigan
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
22 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Patients with medication intractable epilepsy who are recommended to undergo brain surgery to remove a "seizure" focus * Can provide informed consent for the study and willing to participate
Exclusion criteria
* Presence of a permanent electronic implant * Any chronic medical conditions that prevent safe placement of electrodes
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Characterization of time-frequency data | During a 20 minute research phase of a clinically indicated surgery | From recording electrodes |
| Characterization of local field responses (LFPs) | During a 20 minute research phase of a clinically indicated surgery | From recording electrodes |
Countries
United States
Contacts
CONTACTRon Ball
PRINCIPAL_INVESTIGATORMatthew Willsey, MD, PhD
University of Michigan
Outcome results
None listed