Anterior Chamber Angle, Goniotomy, Optical Coherence Tomography, Primary Congenital Glaucoma, Trabeculotomy
Conditions
Brief summary
The research aimed to improve surgical techniques and long-term outcomes by utilizing this advanced imaging technology to illuminate the structural abnormalities of the anterior segment in eyes with primary congenital glaucoma.
Detailed description
Primary congenital glaucoma (PCG) is a rare disease, but it is responsible for 2.5%-15% of all documented cases of pediatric blindness. The main target of the treatment of pediatric glaucoma is to control the IOP surgically. However, medical treatment could be instituted as a temporary and/or adjunctive option to maximize Intraocular pressure (IOP) control. Initial goniotomy or trabeculotomy have been detected to have high success rates. Trabeculotomy has a comparable long-term success rate in most patients of PCG. The success rate of trabeculotomy is lower in advanced or late-presenting patients.
Interventions
PROCEDUREOptical coherence tomography
Infants underwent optical coherence tomography.
Sponsors
Cairo University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
1 Weeks to 72 Weeks
Healthy volunteers
No
Inclusion criteria
* Age from 1 to 72 weeks. * Both sexes. * Infants with primary congenital glaucoma.
Exclusion criteria
* Eyes in which the angle could not be visualized by the handheld anterior segment optical coherence tomography (HH AS-OCT). * Eyes with previous intraocular surgery.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Central corneal thickness | 6 months post-procedure | Central corneal thickness was measured using handheld anterior segment optical coherence tomography (HH AS-OCT). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Trabecular-iris angle | 6 months post-procedure | Trabecular-iris angle was measured using handheld anterior segment optical coherence tomography (HH AS-OCT). |
| Iris thickness | 6 months post-procedure | Iris thickness was measured using handheld anterior segment optical coherence tomography (HH AS-OCT). |
Countries
Egypt
Outcome results
None listed