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Optimization of Transport and Use of a Mobile ECMO Team in Patients With Sudden Cardiac Arrest in the Moravian-Silesian Region

Proposal for the Organisation of the Procedure for Extracorporeal Cardiopulmonary Resuscitation of Patients With Sudden Cardiac Arrest in the Pre-hospital Environment of the Moravian-Silesian Region

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07009652
Enrollment
100
Registered
2025-06-06
Start date
2025-05-01
Completion date
2028-05-01
Last updated
2025-06-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Arrest, Cause Unspecified, Cardiac Arrest With Successful Resuscitation

Keywords

cardiac arrest, extracorporeal membrane oxygenation, out-of-hospital cardiac arrest, extracorporeal cardiopulmonary resuscitation

Brief summary

This study evaluates the feasibility of implementing a mobile extracorporeal membrane oxygenation (ECMO) team and optimizing patient transport logistics.

Detailed description

The aim of the study is to improve neurological outcomes in out-of-hospital cardiac arrest (OHCA) cases in the Moravian-Silesian Region. By analysing regional epidemiological and demographic data, the project aims to identify key factors for reducing the time from collapse to the initiation of ECMO and to support the development of effective protocols for extracorporeal cardiopulmonary resuscitation (ECPR).

Interventions

Extracorporeal cardiopulmonary resuscitation (commonly known as ECPR) is a method of cardiopulmonary resuscitation (CPR) that passes the patient's blood through a machine in a process to oxygenate the blood supply.

Sponsors

Emergency Medical Services, Moravian-Silesian Region
CollaboratorUNKNOWN
University Hospital Ostrava
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
3 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* out-of-hospital cardiac arrest * indication for ECPR

Exclusion criteria

* death at the scene of the accident * withdrawal of the informed consent

Design outcomes

Primary

MeasureTime frameDescription
Neurological outcome after 30 days (CPC score)30 daysAssessment of the neurological status of patients 30 days after the event using the Cerebral Performance Category (CPC) scale, which measures the extent of neurological impairment: * CPC 1 = good neurological condition * CPC 2 = mild impairment * CPC 3-5 = serious impairment, vegetative state or death The primary endpoint of the study is the proportion of patients with a favourable neurological outcome (CPC 1-2).

Secondary

MeasureTime frameDescription
Time from collapse to initiation of ECMOUp to 2 hoursMeasuring the time (in minutes) from patient collapse to ECMO initiation. The aim is to analyse how this time affects neurological outcome.
Transport time to the ECMO centreUp to 2 hoursMeasurement of the time (in minutes) from the arrival of the Emergency Medical Services (EMS) at the scene to the admission of the patient to the ECMO centre.
Arrival time for the mobile ECMO team to the sceneUp to 2 hoursTime interval (in minutes) from activation of the mobile ECMO team to its arrival at the scene. The aim is to evaluate the effectiveness of the model and the potential time benefit of intervention in the field.

Countries

Czechia

Contacts

Primary ContactJiří Hynčica
jiri.hyncica@fno.cz0042059737

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026