Cardiac Arrest, Cause Unspecified, Cardiac Arrest With Successful Resuscitation
Conditions
Keywords
cardiac arrest, extracorporeal membrane oxygenation, out-of-hospital cardiac arrest, extracorporeal cardiopulmonary resuscitation
Brief summary
This study evaluates the feasibility of implementing a mobile extracorporeal membrane oxygenation (ECMO) team and optimizing patient transport logistics.
Detailed description
The aim of the study is to improve neurological outcomes in out-of-hospital cardiac arrest (OHCA) cases in the Moravian-Silesian Region. By analysing regional epidemiological and demographic data, the project aims to identify key factors for reducing the time from collapse to the initiation of ECMO and to support the development of effective protocols for extracorporeal cardiopulmonary resuscitation (ECPR).
Interventions
Extracorporeal cardiopulmonary resuscitation (commonly known as ECPR) is a method of cardiopulmonary resuscitation (CPR) that passes the patient's blood through a machine in a process to oxygenate the blood supply.
Sponsors
Study design
Eligibility
Inclusion criteria
* out-of-hospital cardiac arrest * indication for ECPR
Exclusion criteria
* death at the scene of the accident * withdrawal of the informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Neurological outcome after 30 days (CPC score) | 30 days | Assessment of the neurological status of patients 30 days after the event using the Cerebral Performance Category (CPC) scale, which measures the extent of neurological impairment: * CPC 1 = good neurological condition * CPC 2 = mild impairment * CPC 3-5 = serious impairment, vegetative state or death The primary endpoint of the study is the proportion of patients with a favourable neurological outcome (CPC 1-2). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time from collapse to initiation of ECMO | Up to 2 hours | Measuring the time (in minutes) from patient collapse to ECMO initiation. The aim is to analyse how this time affects neurological outcome. |
| Transport time to the ECMO centre | Up to 2 hours | Measurement of the time (in minutes) from the arrival of the Emergency Medical Services (EMS) at the scene to the admission of the patient to the ECMO centre. |
| Arrival time for the mobile ECMO team to the scene | Up to 2 hours | Time interval (in minutes) from activation of the mobile ECMO team to its arrival at the scene. The aim is to evaluate the effectiveness of the model and the potential time benefit of intervention in the field. |
Countries
Czechia