Precancerous Cervical Lesion
Conditions
Keywords
PDT, HPV, CIN 3
Brief summary
To investigate the efficacy and safety of photodynamic therapy (20% 5-amino-ketovalerate 630nm red light) in the treatment of cervical intraepithelial neoplasia 3(CIN 3)in women in the real world
Interventions
PROCEDUREALA-PDT
use ALA\_PDT to treat the disease
Sponsors
Peking University Third Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* CIN3, photodynamic therapy was required, * type 1 2 transformation area, colposcopy was sufficient * the lesion boundary was completely visible * The ECC did not indicate high-grade lesions
Exclusion criteria
* coexistence or suspicion of cancer; * TCT HSIL * involving glands * Porphyria patients, or suspected allergic to red and blue light. * severe medical comorbidities；
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Efficacy of the treatment | 1 month after the treatment | colposcopy and biopsy will be performed one month after the treatment. Patients will be categorised as having complete remission(CR) if biopsy confirmed LSIL. If CIN 2 was found after the first course of PDT, it would be categorised as partial remission(PR). Those with the same grade were categorised as persistent disease(PD). The proportion of CR after PDT treatment. |
Countries
China
Contacts
Primary ContactQin Han
Outcome results
None listed