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Inferior Alveolar Nerve Lateralization With Simultaneous Implant Placement in Atrophic Posterior Mandible

Evaluation of Neurosensory Function of Inferior Alveolar Nerve Following Lateralization With Sticky Bone Versus Nil Using Computer Guided Dental Implant Placement: A Randomized Clinical Trial

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07008534
Enrollment
18
Registered
2025-06-06
Start date
2025-07-01
Completion date
2027-04-30
Last updated
2025-07-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Implant

Brief summary

The aim of this study is to evaluate the effect of sticky bone on acceleration of recovery of the neurosensory dysfunction of the inferior alveolar nerve following inferior alveolar nerve lateralization surgery for implant placement in patients with posterior vertical bone deficiency in order to overcome the main disadvantage of this technique & provide a reliable,saving time - computer guided simultaneous implant placement- and improved technique.

Detailed description

Lateralization of IAN allows simultaneous implant placement with longer implants and primary stability.2 IAN lateralization provides an option to avoid costly, prolonged bone graftt and also healing periods can be reduced by this option of treatment Vestibular depth remains intact as there is no augmentation in the underlying bone defect. 2 IAN lateralization technique has also some advantages such as less morbidity and less of peri-implant disease.2 In case of the IAN is located in the superior part of the body of the mandible , and presence of mild atrophy of the edentulous alveolar ridge will fetch the alveolar ridge in a close relation to the neuro-vascular bundle, The incidence of high IAN locations ranges from 14.6 to 30.7%. 1However there is some complications such as numbness after surgery which is considered as the most common one also prevent thermal conductivity via implants(Kahnberg et al., 2000) so sticky bone is going to be used to act as an insulator between dental imlants & Inferior alveolar nerve and it contains a number of growth factors so it is predicted to play an important role to enhance recovery of the inferior alveolar nerve after surgery

Interventions

PROCEDUREPatients receiving computer-guided immediate implant placement and inferior alveolar nerve (IAN) lateralization only.

Standard procedure without Sticky Bone application.

PROCEDUREIAN lateralization with computer-guided immediate implant placement using Sticky Bone

The same as the control with additional application of Sticky Bone as an insulator for enhanced neurosensory disfunction

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* Adult patients requiring oral rehabilitation with dental implants in vertically atrophied * Posterior mandibular region, less than 8mm of bone above the mandibular canal. * Patients should be free from any systemic conditions that may affect normal healing. * Absence of any pathological conditions involving mandibular bones.

Exclusion criteria

* Patients under bisphosphonates treatment. * Any contraindication for general anaesthesia. * Osteoporotic patients. * Patients with neurological disorders (neuralgias, Parkinson' s disease). * Patients with systematic disease that may complicate healing.

Design outcomes

Primary

MeasureTime frame
Clinical neurosensory assessment of inferior alveolar nerve.6 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026