Postoperative Complications, Preoperative Nutritional Markers
Conditions
Brief summary
This prospective observational study aims to evaluate whether preoperative immune-nutritional markers-specifically the Prognostic Nutritional Index (PNI), HALP score, Neutrophil-to-Lymphocyte Ratio (NLR), and C-Reactive Protein (CRP)-can predict early postoperative clinical outcomes such as time to oral intake, mobilization, complications, and length of hospital stay in patients undergoing elective laparoscopic sleeve gastrectomy.
Interventions
OTHERNutritional and Inflammatory Marker Evaluation
This is a prospective observational cohort study evaluating whether preoperative immune-nutritional markers-including Prognostic Nutritional Index (PNI), HALP score, Neutrophil-to-Lymphocyte Ratio (NLR), and C-Reactive Protein (CRP)-can predict early postoperative clinical outcomes (complication development, time to oral intake, mobilization, and length of hospital stay) in patients undergoing elective laparoscopic sleeve gastrectomy. No intervention or treatment is administered as part of this study. All data are collected from routine preoperative laboratory tests and standard postoperative clinical follow-up.
Sponsors
Istinye University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Age between 18 and 65 years * Body mass index (BMI) ≥ 35 kg/m² * Scheduled for elective laparoscopic sleeve gastrectomy * Availability of complete preoperative laboratory test results * Signed informed consent
Exclusion criteria
* Severe hepatic or renal dysfunction * Presence of active infection * History of immunosuppressive therapy or hematologic malignancy * Need for intensive care unit (ICU) admission within the first 72 hours postoperatively * Preoperative administration of albumin or blood products
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Occurrence of Postoperative Complications Within 72 Hours | Up to 72 hours after surgery | Complications such as fever, surgical site infection, nausea/vomiting, hypotension, or need for reintervention will be recorded during the first 72 hours after laparoscopic sleeve gastrectomy. The association between preoperative nutritional and inflammatory scores (PNI, HALP, NLR, CRP) and complication occurrence will be evaluated. |
Countries
Turkey (Türkiye)
Contacts
Primary Contactilke dolgun
Backup Contactilke dolgun
Outcome results
None listed