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SMCs With LVH Compared to HCM

Patients With Left Ventricular Hypertrophy in Syndromic and Metabolic Cardiomyopathy Compared to Hypertrophic Cardiomyopathy: an Age-sex Matched Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07006974
Enrollment
165
Registered
2025-06-05
Start date
2025-05-27
Completion date
2025-12-31
Last updated
2026-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiomyopathies, Syndromic and Metabolic Cardiomyopathy

Brief summary

The goal of this cohort study is to investigate the clinical characteristics of SMCs and to explore the difference in cardiovascular outcomes in comparison to age-, sex-, and admission year-matched HCM patients. The main question it aims to answer is: * Do patients with SMCs have higher rates of cardiac outcomes? * What risk factors do SMCs patients experience a poor prognosis?

Interventions

OTHERSMCs

patients with SMCs

Sponsors

China National Center for Cardiovascular Diseases
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* patients who were diagnosed SMCs or HCM. Gene testing and muscle biopsy were used to confirm the diagnosis of SMCs. The diagnose of HCM was according to the 2024 ESC Guidelines of HCM but without evidence of SMCs. * complete baseline data * accessible follow-up data

Exclusion criteria

* incomplete baseine data

Design outcomes

Primary

MeasureTime frameDescription
primary outcome3 yearsa composite of all-cause death, hospitalization for heart failure, myocardial infarction, ischemia or hemorrhagic stroke (excluding transient ischemic attack), other thrombotic events, and modified International Society on Thrombosis and Haemostasis crit

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026