Total Knee Arthroplasty
Conditions
Brief summary
This multicenter research project aims to correlate objective testing of muscle mass, muscle strength, neuromuscular activation, walking speed and other functional tests with everyday activity and subjective quality of life after total knee arthroplasty. For this purpose, 400 patients from 5 orthopedic departments in Germany and USA will be examined at the time points pre-op, six weeks, three, six and 12 months post-op.
Interventions
OTHERReturn to Activity Battery
The main target parameters are muscle mass (sonography), muscle strength (isometric maximum strength measurement), neuromuscular activation (surface EMG), functionality (e.g. 6MWT, chair rising test), knee swelling and subjective assessment of everyday and leisure activities, quality of life (e.g. SF-36) and return to work
Sponsors
University Hospital, Bonn
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients receiving a total knee arthroplasty * Ability to perform the return to activity battery
Exclusion criteria
* Inability to perform the return to activity battery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Muscle Mass | Pre-OP to 12 months Post-OP | Sonographically Analysis of the M. quadriceps femoris |
| Muscle Strength | Pre-OP to 12 Months Post-OP | Isometric maximal strength of the knee extensors |
Countries
Germany
Outcome results
None listed