Symptomatic and Incidental RCC Detection

Assessment of Symptomatic and Incidental Detection of Renal Cell Carcinoma Using Standard Imaging Modalities

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07004426

Acronym

KIDCaD

Enrollment

1000

Registered

2025-06-04

Start date

2025-06-01

Completion date

2025-07-15

Last updated

2026-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign Renal Neoplasm, Renal Carcinoma, Renal Cell Carcinoma (Kidney Cancer)

Keywords

Renal cell carcinoma, Detection, Imaging modalities, Non-neoplastic renal lesions

Brief summary

Evaluation of the frequency of symptomatic and incidental detection of renal carcinoma at different stages depending on the imaging modality used

Detailed description

In the Czech Republic, there is no screening program for renal cell carcinoma. Existing evidence suggests that incidental detection of this cancer tends to occur in its early stages, which are more manageable due to effective treatment options, ultimately reducing renal cancer mortality. This highlights the potential value of evaluating current imaging modalities and determining their role in secondary prevention. This cross-sectional study, based on hospital data, aims to contribute to a better understanding of this issue and to assess the effectiveness of imaging techniques in the early detection of renal cell carcinoma. Furthermore, data analysis may reveal the influence of risk factors on the detection of tumors at various stages.

Interventions

PROCEDURESurgical treatment of renal lesions

Surgical treatment of renal lesions

Study design

Observational model

OTHER

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* patients over 18 years of age undergoing surgical treatment for renal lesions

Exclusion criteria

* patients undergoing surgery for non-renal and urotelial carcinoma, including unknown * patients with recurrent renal lesions

Design outcomes

Primary

Measure	Time frame	Description
Detection-specific renal cell carcinoma (RCC) proportions	From 2011 to 2020	Detection-specific renal cell carcinoma (RCC) proportions, defined as the proportion of each detection type relative to all RCC cases. Results will be stratified by stage, histological type, and imaging modality.

Secondary

Measure	Time frame	Description
Proportion of RCC among neoplastic and non-neoplastic renal lesions	From 2011 to 2020	Proportion of RCC among neoplastic and non-neoplastic renal lesions, stratified by investigated covariates (e.g., age, sex, smoking status, BMI, or hypertension treatment).