Effusion
Conditions
Brief summary
Exudative pleural effusion (EPE) presents a diagnostic challenge, requiring accurate biomarkers to predict outcomes and guide treatment. The neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) in pleural fluid are emerging as potential prognostic markers. We aimed to assess the diagnostic and prognostic utility of pleural fluid NLR and MLR in EPE.
Detailed description
Pleural fluid NLR and MLR are reliable biomarkers for diagnosing malignant pleural effusion and predicting poorer survival outcomes. These ratios may be useful in clinical practice, especially in resource-limited settings, to guide decision-making in the management of pleural effusions.
Interventions
PROCEDUREmedical thoracoscopy
pleural fluid aspiration and cellular analysis
Sponsors
Alexandria University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Months to No maximum
Healthy volunteers
No
Inclusion criteria
* adult patients aged 18-80 years with an EPE diagnosis confirmed by thoracentesis.
Exclusion criteria
*
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MLR and NLR measuring in pleural fluid | 1 month | counting pleural fluid monocytes,lymphocytes and neutrophils |
Other
| Measure | Time frame | Description |
|---|---|---|
| MLR and NLR measuring in pleural fluid | one month | counting the pleural monocytes, neutrophils and lymphoctes |
Countries
Egypt
Outcome results
None listed