Cancer, Tumor
Conditions
Brief summary
The purpose of this study is to obtain unused resected tumor tissue sample and associated clinical data from patients enrolled in this study to research ex vivo treatment response and integrity of tumor microenvironment using omics analysis and imaging while maintaining cell stability in a live environment.
Interventions
OTHERNo intervention
Lab-based correlative study; no intervention
Sponsors
Mayo Clinic
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Ability to understand and sign informed consent * Planning to undergo a surgical procedure to remove cancer
Exclusion criteria
* Does not meet Inclusion criteria * No tissue for research available at time of surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tissue response to treatment | Up to 72 hours | Tumor sample fragments will be treated with various combination of chemotherapy and immunotherapy drugs that are commonly used to treat patients clinically (panel of drugs will be selected based on cancer type). response to the treatment will be assessed at multiple timepoints during a 72-hour period. |
Countries
United States
Contacts
CONTACTClinical Trials Referral Office
CONTACTMegan Warner
PRINCIPAL_INVESTIGATORDebabrata Mukhopadhyay, PhD
Mayo Clinic
Outcome results
None listed