Endometriosis
Conditions
Brief summary
This study investigates epigenetic changes in menstrual effluent and plasma from women with endometriosis to identify potential non-invasive diagnostic biomarkers for the disease.
Interventions
PROCEDUREEndometrial biopsy or menstrual cup and blood sample
Enrolled patients will give their menstrual effluent either via a menstrual cup or via a pipelle biopsy. They will also undergo a blood draw.
Sponsors
Université Catholique de Louvain
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 56 Years
Healthy volunteers
Yes
Inclusion criteria
* Premenopausal * In spontaneous menstrual cycle (no hormonal treatments for the last 3 months) * Healthy or with a clear diagnosis of endometriosis via ultrasound, MRI or laparoscopy
Exclusion criteria
* HIV or Hepatitis positive * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Epigenetic analysis | Throughout the entire study, approximately during 3,5 years | Histone post-translational modifications |
Countries
Belgium
Contacts
Primary ContactMarie-Madeleine Dolmans, MD, PhD
Outcome results
None listed