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The Swallowing Function of Oral Cancer Surgery

A Longitudinal Study on Dysphagia and Associated Nutritional Complications Following Oral Cancer Surgery

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07000032
Enrollment
75
Registered
2025-05-31
Start date
2025-06-15
Completion date
2032-12-31
Last updated
2025-05-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The Swallowing Changes

Keywords

oral cancer surgery, swallowing, nutrition

Brief summary

This study enrolled patients who underwent oral cancer resection. Swallowing function, muscle status, and nutritional status were assessed before treatment, one month after treatment, and between three months to one year post-treatment.

Detailed description

Dysphagia is a common and debilitating symptom among patients who undergo oral cancer resection with reconstruction followed by adjuvant radiotherapy. During the course of the disease, approximately 20% to 98% of patients experience swallowing difficulties. This is primarily caused by tumor destruction, postoperative sequelae from surgical resection, and the adverse effects of radiotherapy and chemotherapy. The use of chemotherapy or radiotherapy-particularly when combined-increases the incidence of complications such as oropharyngeal mucositis, odynophagia, dysgeusia, xerostomia, nausea, vomiting, and fatigue. These complications may lead to dehydration and significant weight loss, which in turn negatively impact nutritional status, functional ability, and quality of life. This study enrolled patients who underwent oral cancer surgery. Swallowing function, muscle status, and nutritional status were assessed before treatment, one month after treatment, and between three months to one year post-treatment.

Interventions

OTHERNo Intervention: Observational Cohort

This is an observational cohort

Sponsors

National Taiwan University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patients undergoing oral cancer

Exclusion criteria

* patients unable to unable to cooperate with the examination

Design outcomes

Primary

MeasureTime frameDescription
bolus presence timeone year after surgeryThe opening of hypopharynx

Contacts

Primary ContactChih-Jun Lai, MD, PhD
littlecherrytw@gmail.com+886-972652086

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026