Aged, Hypoalbuminemia, Malnutrition, Neoplasms, Postoperative Complications
Conditions
Brief summary
This retrospective, single-center study aims to evaluate the impact of preoperative albumin levels on postoperative outcomes in geriatric patients (aged 65 and above) undergoing cancer surgery. The study will compare postoperative complication rates, length of hospital stay, and intensive care needs between patients with hypoalbuminemia and those with normal albumin levels.
Detailed description
Malnutrition is a significant risk factor for postoperative complications in elderly cancer patients. Preoperative serum albumin is a key biomarker reflecting nutritional and inflammatory status. This study will retrospectively review the medical records of 330 geriatric patients (≥65 years) who underwent cancer surgery at Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital. Patients will be grouped according to preoperative albumin levels: Group 1 (\<3.5 g/dL, hypoalbuminemia) and Group 2 (≥3.5 g/dL, normal). The primary aim is to compare postoperative complication rates, length of hospital stay, and intensive care requirements between these groups. The findings are expected to clarify the prognostic value of albumin and support individualized perioperative management in geriatric cancer surgery.
Interventions
None listed
Sponsors
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Age 65 years or older * Diagnosed with cancer and underwent cancer surgery * Preoperative albumin level recorded before surgery
Exclusion criteria
* Preoperative sepsis, severe infection, or active inflammatory disease * Emergency or palliative surgery * Missing preoperative albumin value * Incomplete medical records or follow-up data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative Complication Rate | within 30 days after surgery | The proportion of patients experiencing any postoperative complication (including but not limited to pulmonary complications, infections, or other adverse events) within 30 days after surgery, as assessed by clinical records and standardized criteria (e.g., Clavien-Dindo classification) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Length of Hospital Stay | postoperative first 30 days | Total number of days from the date of surgery to hospital discharge. |
| Postoperative Intensive Care Unit (ICU) Admission | immediately after the surgery | The proportion of patients requiring ICU admission after surgery |
| Length of ICU Stay | 30 days after surgery | The total duration of ICU stay following surgery |
| 30-day Postoperative Mortality | within 30 days after surgery | All-cause mortality within 30 days after surgery |
| Incidence of Specific Postoperative Pulmonary Complications | 30 days after surgery | The number of patients developing pulmonary complications (e.g., pneumonia, pleural effusion, atelectasis, ARDS, respiratory failure) within 30 days after surgery |
Countries
Turkey (Türkiye)
Contacts
PRINCIPAL_INVESTIGATORMustafa Kemal SAHIN
MUSTAFA KEMAL SAHİN
Outcome results
None listed