Episodic Migraine, Greater Occipital Nerve Block, Sphenopalatine Ganglion Block
Conditions
Brief summary
This study compares the effectiveness of greater occipital nerve blockade and sphenopalatine ganglion blockade in reducing headache intensity, duration, frequency, and disability in patients with episodic migraine.
Detailed description
Migraine is a chronic neurological disorder characterized by recurrent headaches, affecting millions globally. Peripheral nerve blocks such as Greater Occipital Nerve (GON) and Sphenopalatine Ganglion (SPG) blockade have emerged as promising non-pharmacologic treatments.
Interventions
Patients will receive greater occipital nerve blockade using 2 mL of 2% lidocaine at the medial one-third of the line between the occipital protuberance and mastoid process.
OTHERSphenopalatine ganglion blockade
Patients will receive greater sphenopalatine ganglion blockade using 2 mL of 2% lidocaine using a transnasal approach with a cotton swab inserted along the superior middle turbinate to the posterior nasopharyngeal wall.
Sponsors
New Valley University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Adults aged 18-65 years. * Both sexes. * Diagnosed with episodic migraine per the International Classification of Headache Disorders, 3rd edition (ICHD-3). * Failure to achieve adequate relief with at least one prophylactic migraine treatment.
Exclusion criteria
* Chronic migraine (≥15 headache days per month). * History of nerve blocks within the last 6 months. * Known allergy to anesthetic agents. * Pregnancy or lactation. * Active psychiatric conditions affecting compliance.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Degree of headache intensity | 3 months post-procedure | Reduction in headache intensity will be recorded using numeric rating scale (NRS). Each patient will be instructed about pain assessment with NRS score. NRS (0 represents no pain while 10 represents the worst pain imaginable). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Migraine disability assessment score | 3 months post-procedure | The migraine disability assessment scores are as follows: little or no disability, 5 to 10; moderate disability, 1 to 20; and severe disability, more than 20. |
| Headache duration | 3 months post-procedure | Headache duration will be recorded. |
| Headache frequency | 3 months post-procedure | Headache frequency will be recorded. |
Countries
Egypt
Outcome results
None listed