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Medical Marijuana and Open Road Driving Task

An Open Road Driving Performance Task to Examine Long-term Medical Marijuana Use and Prescription Opioid Positivity in Adults 50 and Older

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06995937
Acronym
ROADACE
Enrollment
250
Registered
2025-05-30
Start date
2025-05-19
Completion date
2029-01-30
Last updated
2026-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Medical Cannabis

Brief summary

Medical marijuana use among adults 50 and older has more than doubled in the past decade with exponential increases projected in this demographic by 2050, and prescription opioids are one of the most common treatments for pain management in this population. To date, no studies systematically assess driving performance in a rigorous and ecologically valid manner accounting for long-term medical marijuana use and/or the combined effect of prescription opioid use in adults 50 and older who endorse chronic or severe non-malignant pain. Further, studies examining how older adults self-regulate prescription medication use and driving behavior is limited, with none rigorously examining medical marijuana.

Interventions

None listed

Sponsors

Florida State University
Lead SponsorOTHER
University of Florida
CollaboratorOTHER
National Institute on Drug Abuse (NIDA)
CollaboratorNIH

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Age 50 and older who endorse chronic or severe non-malignant pain * Resident of Florida with an active and valid Florida Drivers License * Can communicate in English * Willing and able to complete study procedures * Have active medical marijuana card for \>12 months issued by the state of Florida (MMG group) OR are race-sex match who has not used marijuana in the past 10 years with no history of daily use (NMG group)

Exclusion criteria

* Have active psychosis * Have lost or revoked driving privileges * Score of below the cut 24 (out of 30) on the Montreal Cognitive Assessment (MoCA) * Are a control participant who urine test positive for marijuana use and/or reports any marijuana use in past 10 years

Design outcomes

Primary

MeasureTime frameDescription
Sum of Maneuvers Score (SMS)One DayA standardized score sheet with a total of 49 driving maneuvers and eight types of possible driving errors is used by the Certified Driver Rehabilitation Specialist while the participant is driving. The driving errors are lane maintenance errors, speed regulation errors, adjustment-to-stimuli errors, yielding errors, signaling errors, vehicle positioning errors, visual scanning, and gap acceptance errors. For each maneuver, a maximum score of 3 is given if no errors are committed. At the end of the driving course, the sum of the points attained is computed as the sum of maneuvers score (SMS) ranging from 0 to 147, with 147 indicating a perfect driving score (zero errors).

Countries

United States

Contacts

CONTACTNicole Ennis, PhD
nennis@fsu.edu850-274-4032
CONTACTKatie Kloss
katie.kloss@med.fsu.edu850-274-5089

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 21, 2026