Decision Aid
Conditions
Keywords
Lynch syndrome, colorectal cancer, colon cancer, genetic testing
Brief summary
The goal of this study is to understand how people understand risk from genetic testing. The investigators want to understand what visual aid best helps people accurately assess risk. The investigators also want to understand how people relate risk to their health. The main questions the study aims to answer are: 1. Which visual aid most accurately show genetic risk? 2. How do people perceive risk related to genetic test results? 3. What factors are associated with people discussing their results with family? Participants will: 1. receive of of two visual aids showing risk 2. state their estimation of risk 3. answer questions about how they feel about risk and sharing information with family
Detailed description
This study aims to determine what visual aid helps people most accurately interpret risk from genetic test results. The study also examines how people perceive risk using the Tripartite Risk Model. Last, the study examines factors that are associated with intention to share genetic test results with family members. Participants will provide brief sociodemographic information, complete brief health literacy and numeracy assessments, and questions about how they perceive risk. Participants will be informed of a genetic testing scenario and will receive one of two visual aids. After reviewing the visual aid, participants will state the risk shown in the visual aid and will answer questions about their perceived risk and sharing results with family members (blood relatives).
Interventions
BEHAVIORALVisual Array
Single side-by-side visual array
BEHAVIORALNarrative Visual Array
Evolving narrative with sequential visual arrays
Sponsors
Stephanie B. Seminara, MD
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Boston College
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Subject)
Intervention model description
One-to-one randomization into two parallel groups
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* ability to read and understand English * opt-in consent
Exclusion criteria
* incorrect responses to validation questions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Risk Accuracy | immediately after the intervention | closest approximation to risk percentage depicted in the visual array |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Communication Intent | immediately after the intervention | Intent to communicate risk to blood relatives using 7-point Likert-type scale |
| Risk Perceptions | baseline | Perceptions of deliberative, affective, and experiential risk using 7-point Likert-type scales |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORAndrew A Dwyer, PhD
Boston College
Outcome results
None listed