Anxiety, Bipolar Disorder, Depression, Obsessive-compulsive Disorder, Personality Disorder, Psychotic Disorders, PTSD, Schizophrenia
Conditions
Keywords
Pharmacotherapy, Cognitive behavioral psychotherapy, Recovery
Brief summary
The combination of pharmacotherapy and individual cognitive behavioral therapy in a private practice.
Detailed description
Reintegration into society and good functional outcome by people with mental health disorders is frequently the result of the combination of pharmacotherapy and individual cognitive behavioral psychotherapy. The effectiveness and efficacy of this combination of treatments under the recovery perspective by anxiety disorders, depressive disorders, PTSD, bipolar disorders, schizophrenia and psychotic disorders, by obsessive-compulsive disorders and by personality disorders presents the main goal of this research protocol. Recovery means that people learn through the trherapy to be responsible towards their own problems.
Interventions
COMBINATION_PRODUCTGroup A. The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by anxiety disorders and depression.
The combination of pharmacotherapy (anxiolytics (tavor, clonotril, lexotanil), antidepressants (SSRI, SNRI) and individual cognitive behavioral psychotherapy by anxiety disorders and depression.
COMBINATION_PRODUCTGroup B. The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by PTSD
The combination of pharmacotherapy (anxiolytics (tavor, clonotril, lexotanil), antidepressants (SSRI, SNRI) and individual cognitive behavioral psychotherapy by PTSD
COMBINATION_PRODUCTGroup C. The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by obsessive-compulsive disorder.
The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by obsessive-compulsive disorder.
COMBINATION_PRODUCTGroup D.The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by bipolar disorder
The combination of pharmacotherapy (anxiolytics (tavor, clonotril, lexotanil) antidepressants (SSRI, SNRI), mood stabilizers (lithium, depakine), antipsychotics (clozapine and atypical antipsychotics)) and individual cognitive behavioral psychotherapy by bipolar disorder.
COMBINATION_PRODUCTGroup E. The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by schizophrenia and psychotic disorders
The combination of pharmacotherapy (anxiolytics(tavor, clonotril, lexotanil), antidepressants (SSRI, SNRI), antipsychotics (clozapine and atypical antipsychotics)) and individual cognitive behavioral psychotherapy by schizophrenia and psychotic disorders.
COMBINATION_PRODUCTGroup F.The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by personality disorders
The combination of pharmacotherapy (anxiolytics (tavor, clonotril, lexotanil), antidepressants (SSRI, SNRI), antipsychotics (clozapine and atypical antipsychotics) and individual cognitive behavioral psychotherapy by personality disorders.
Sponsors
Rakitzi, Stavroula
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* age 18-65, * IQ ≥ 80, * Diagnosis: anxiety disorders, depression, obsessive-compulsive disorders, PTSD, personality disorders, bipolar disorders, schizophrenia and psychotic disorders.
Exclusion criteria
\*Substance abuse and head injury.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MCCB BACS symbol coding | Preintervention | It measures speed of processing. Minimum 0, maximum 110, high scores better |
| MCCB Wechsler memory scale-spatial span | Preintervention | It measures non-verbal working memory. Minimum 0, maximum 32, high scores better, Summary of forward and backward total score. |
| MCCB Neurospychological Assessment Battery (NAB) | Preintervention | It measures reasoning and problem-solving. Minimum 0, maximum 26. high scores better |
| MCCB Brief visuospatial memory test | Preintervention | It measures visual memory. Sum of Trial 1, 2, 3. Minimum 0, maximum 12. high scores better |
| The Greek verbal memory test | Preintervention | It measures oral verbal memory. Semantic. Sum of the 3 categories divided to 3. Minimum 0, maximum 40. high scores better. |
| SCL-90-R | Preintervention | It evaluates psychopathology. T\>60 means psychopathology. Low scores better |
| PANNS total | Preintervention | It measures positive, negative symptoms and general psychopathology. Minimum 31, maximum 210. Low scores better |
| WHODAS total | Preintervention | It measures functional outcome. Minimum 0, maximum 100. low scores better. |
| RAS-DS total | Preintervention | It measures recovery. Minimum 0, maximum 152. High scores better. |
| The Clinical Global Impression Scale (CGI) | Preintervention | It measures severity of illness. Minimum 0, Maximum 7, low scores better. |
| SRSDA | Preintervention | It measures Depression. Minimum 0, maximum 14 or higher. Low scores better |
| SRSDA B | Preintervention | It measures Anxiety. Minimum 0, maximum 10 or higher. Low scores better |
| Hamilton Depression Scale | Preintervention | It measures depression. Minimum 0, maximum 23. Low scores better. |
| Montgomery and Asperg depression scale | Preintervention | It measures depression. Minimum 0, maximum 60. Low scores better. |
| The Altman self-rating scale | Preintervention | It measures mania. Minimum 0, maximum 6 or higher. Low scores better. |
| The Young mania rating scale | Preintervention | It measures mania. Minimum 0, maximum 60. Low scores better |
| PSYRAT H | Preintervention | It measures psychotic symptoms. Hallucinations. Minimum 0, maximum 24. Low scores better. |
| PSYRAT D | Preintervention | It measures psychotic symptoms. Delusions. Minimum 0, maximum 44. Low scores better |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| WAIS | Preintervention | It measures the Intelligenz-quotient. For bipolar disorder, schizophrenia and psychotic disorders |
Countries
Greece
Contacts
STUDY_DIRECTORDr. Stavroula Rakitzi, PhD
Private Practice
STUDY_DIRECTORDr. Polyxeni Georgila, M. D.
Private Practice
Outcome results
None listed