Colonoscope Passage
Conditions
Keywords
colonoscope passage, left colon water exchange, cap-assisted, without loop formation
Brief summary
A prospective, single-center, single-blind, randomized controlled study to compare the proportion of straight passage through the sigmoid colon without loop formation between conventional colonoscope passage, left colon water exchange colonoscope passage, and cap-assisted left colon water exchange colonoscope passage through the sigmoid colon
Detailed description
1. Patients are undergone screening, surveillance, or therapeutic colonoscopy at the Endoscopy department of Gastrointestinal endoscopy center of Huadong hospital affiliated to Fudan University. 2. Randomize patients into 3 interventional groups based on R script (version 4.4.1), including (1) Group 1: Conventional colonoscope passage, (2) Group 2: left colon water exchange colonoscope passage, (3) Group 3: cap-assisted left colon water exchange colonoscope passage. 3. Collecting variables which consist of primary and secodary outcomes.
Interventions
PROCEDUREConventional colonoscope passage
Use conventional colonoscope passage through the sigmoid colon
PROCEDUREleft colon water exchange colonoscope passage
Use left colon water exchange colonoscope passage through the sigmoid colon
PROCEDUREcap-assisted left colon water exchange colonoscope passage
Use cap-assisted left colon water exchange colonoscope passage through sigmoid colon
Sponsors
Fudan University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* aged 18-80 years * sedation colonoscopy
Exclusion criteria
* History of colorectal surgery * Clinical suspicion of, or pathologically confirmed, colorectal cancer * Presence of any alarm symptom or sign-hematochezia, melena, unexplained anemia or weight loss, palpable abdominal mass, or a positive digital rectal examination * Pregnancy or lactation * Known or suspected gastrointestinal obstruction * Diagnosed inflammatory bowel disease * Use of antiplatelet or anticoagulant therapy (e.g., aspirin, warfarin) within 7 days before colonoscopy or any documented coagulation disorder * Current enrolment in another clinical study or participation in any clinical trial within the previous 60 days * Requirement for emergency colonoscopy * Any other condition that, in the investigators' judgment, renders the patient unsuitable for inclusion in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of straight passage through the sigmoid colon without loop formation | immediately after the procedure |
Secondary
| Measure | Time frame |
|---|---|
| Cecal intubation rate | immediately after the procedure |
| Cecal intubation time | immediately after the procedure |
| Time of insertion to cecum | immediately after the procedure |
| Colonoscope insertion failure rate | immediately after the procedure |
| Adenoma detection rate | 2 weeks after the procedure |
Countries
China
Contacts
Primary ContactDanian Ji, M.D.
Backup ContactZhiyu Dong, M.D.
Outcome results
None listed