Central Corneal Thickness, Endothelial Cell Density Loss, Hard Nuclear Cataract, Phacoemulsification Cataract Surgery
Conditions
Keywords
Hard nuclear cataract, phacoemulisification mode, ultrasound time, cumulative dissipated energy
Brief summary
In this study, we compared two types of phacoemulsification commonly used in cataract surgery to evaluate their effect on the prognosis of patients with hard nuclei. This will provide a theoretical basis for selecting a more appropriate cataract surgery modality in practice in hard-nucleus patients.
Detailed description
In this study, we randomized patients into two groups. One group was the combined mode group in burst mode and the other group was the torsional ultrasound group in continuous mode. Cumulative dissipated energy(CDE) and ultrasound time(UST) were recorded during the procedure. Changes in central cornea thickness(CCT) and endothelial cell density(ECD) of the patients were recorded postoperatively during a 3-month follow-up. Intraoperative and postoperative complications were also recorded. The above data were analyzed to compare the effect of both on postoperative corneal recovery in patients with hard nuclei.
Interventions
PROCEDUREcombined burst mode
the combined burst mode is commonly used in cataract phacoemulsification. This study compares whether the two modes have different outcomes in hard nuclear cataract surgery.
PROCEDUREtorsional mode
the toesional mode is commonly used in cataract phacoemulsification. This study compares whether the two modes have different outcomes in hard nuclear cataract surgery.
Sponsors
Eye & ENT Hospital of Fudan University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Intervention model description
all individuals scheduled for cataract surgery were randomly allocated to either the combined mode group (Burst Tor+ Burst US, Group A) or the torsional mode group (Linear Tor, Group B), utilizing an online random number generator.
Eligibility
Sex/Gender
ALL
Age
50 Years to 95 Years
Healthy volunteers
No
Inclusion criteria
* patients with age-related cataracts that were only classified by Emery-Little as nuclear hardness grade III-V. * encompassed a minimum dilated pupil diameter of 7 mm or above, as well as a corneal endothelial cell count exceeding 1200/mm\^2. * Corneal morphology is normal and clear * Informed consent is required prior to enrollment
Exclusion criteria
* Those with white cataracts, histories of eye surgery, and eye diseases such as corneal pathology, uveitis, Fuchs' dystrophy, and glaucoma were excluded. * Exclude those with comorbid ocular and systemic diseases that affect corneal endothelial cell function * Exclude those with previous intraocular surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Endothelial cell density | At 1day, 1week, 1month, 3months postoperatively. | Endothelial cell density after cataract surgery. |
| central cornea thickness | At 1day, 1week, 1month, 3months postoperatively. | central cornea thickness after cataract surgery. |
| ultrasound time | During cataract surgery | ultrasound time during phacoemulsification. |
| cumulative dissipated energy | During cataract surgery | cumulative dissipated energy during phacoemulsification. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| occlusion | during surgery | occlusion during phacoemulsification |
| best-corrected distance visual acuity | At 1day, 1week, 1month, 3months postoperatively. | best-corrected distance visual acuity after cataract surgery |
| cornea edema | At 1day, 1week, 1month, 3months postoperatively. | cornea edema after cataract surgery |
Countries
China
Outcome results
None listed