Cancer, Geographic Tongue
Conditions
Keywords
antiangiogenic drugs, glossitis benign migratory
Brief summary
Oral clinical descriptions related to adverse events in patients treated with those elective multi-targeted receptor tyrosine kinase inhibitors and a recombinant humanised monoclonal antibody
Detailed description
Electronical medical and dental records, high-resolution digital photograph were reviewed. Demographic data, medical background, clinical and laboratory information were recorded for each individual case.
Interventions
OTHERClinical evaluation
treatment methods, associated symptoms, evolution and clinical presentation
Sponsors
Instituto do Cancer do Estado de São Paulo
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* patient's charts which underwent antiangiogenic targeted drugs
Exclusion criteria
* chemoterapy without angiogenesis inhibitors
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Benign migratory glossitis | From enrollment to the end of study at 7 years | erythematous erosions, with loss of filiform papillae, surrounded by white circinate rims on the dorsal tongue |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Adverse events | From enrollment to the end of study at 7 years | Dysgeusia , dermatologic toxicities such as skin erythemas and vesicles on the palms of the hands and burning sensation |
Countries
Brazil
Outcome results
None listed