Study of the Use of Non-invasive Ventilation in Bronchial Dilatation Disease

Study of the Use of Non-invasive Ventilation in Bronchial Dilatation Disease (BRONCHINIV)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06987461

Acronym

BRONCHINIV

Enrollment

Registered

2025-05-23

Start date

2025-01-06

Completion date

2025-12-31

Last updated

2025-05-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchectasie, Bronchial Dilatation Disease

Keywords

bronchial dilatation disease, Non-invasive ventilation, efficiency

Brief summary

This is a medical record data collection study. The goal of this non-interventional and retrospective study is to describe the characteristics of the population currently being monitored for bronchial dilatation who have been treated with long-term NIV. This is a study based on data from medical records. The assessment criteria will be : * Epidemiological characteristics of the population with bronchial dilatation on long-term NIV * Reasons for initiation of NIV * NIV adjustment methods

Detailed description

Non-invasive ventilation is a treatment sometimes used for severe severe bronchial dilatation, but to date there are no studies its efficacy. The expected results in this context are : * a description of the characteristics of patients with severe bronchial on non-invasive ventilation (NIV) * a better understanding, during NIV management, of the settings used, the tolerance and effectiveness of NIV in reducing exacerbations, hospital admissions and patient mortality. * move towards better patient management Data will be extracted from patient medical records and the PMSI.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients over 18 years * Predominant diagnosis of bronchiectatic disease, excluding cystic fibrosis, confirmed by computed tomography * Introduction of long-term NIV at a given point in the patient's care

Exclusion criteria

* Patient's opposition to participating in this study * Cystic fibrosis * Predominant diagnosis of COPD or asthma, traction bronchiectasis, bronchiectasis resulting from focal endobronchial lesion, sarcoidosis or active allergic bronchopulmonary aspergillosis.

Design outcomes

Primary

Measure	Time frame
epidemiological characteristics of the population with bronchial dilation under long-term NIV	Through study completion, an average of 1 year
Reasons for placing under NIV	Through study completion, an average of 1 year
Non-invasive ventilation adjustment modalities	Through study completion, an average of 1 year

Secondary

Measure	Time frame
Number of acute exacerbations (according to international recommendations) after initiation of NIV	Through study completion, an average of 1 year
Stabilization of respiratory functional tests evolution of FEV1 (%, slope) of PaCO2	Through study completion, an average of 1 year

Countries

France

Contacts

Primary ContactSuela DEMIRI, Doctor, Hospital Practitioner

suela.demiri@chicreteil.fr01 57 02 29 63

Outcome results