Comparison of the Effects of Sugammadex and Neostigmine on Early Extubation, Intensive Care Unit Admission and Length of Stay, and Hospital Costs in Adult Cranial Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06987357

Enrollment

112

Registered

2025-05-23

Start date

2021-05-01

Completion date

2021-07-31

Last updated

2025-05-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Craniectomy, Extubation, Hospital Costs, Recovery After Neuromuscular Block, Sugammadex

Brief summary

The aim of this study was to retrospectively investigate the effects of sugammadex or neostigmine, which are routinely used after the completion of surgery to antagonize (reverse) neuromuscular blockade in adult patients undergoing cranial surgery under general anesthesia, on early extubation in the operating room, intensive care unit admission and length of stay, length of hospital stay, and hospital costs.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

19 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients from the American Society of Anesthesiology (ASA) I-II-III group, * over the age of 18, * who underwent elective surgery, * underwent general anesthesia with sevoflurane anesthesia from volatile anesthetics, * used rocuronium as a neuromuscular blocking agent

Exclusion criteria

* Patients aged 18 and under, * ASA IV and above, * who underwent surgery under emergency conditions, * who have incomplete follow-up form records and electronic media data, * who were taken to the intensive care unit without neuromuscular blockade antagonism due to long surgery, * who were treated with a neuromuscular blocking agent other than rocuronium, * who were treated with a volatile anesthetic other than sevoflurane or with total intravenous anesthesia.

Design outcomes

Primary

Measure	Time frame
The amount of cost in the hospital process	through study completion, an average of 3 month
Length of stay in the intensive care unit	through study completion, an average of 3 month
Early extubation rate after two different neuromuscular blocking antagonist drugs	through study completion, an average of 3 month

Countries

Turkey (Türkiye)

Outcome results