Chronic Rhinosinusitis (Diagnosis), Low Level Laser Therapy, Photobiostimulation, Pulsed Electromagnetic Filed, Quality of Life
Conditions
Brief summary
This study was done to find out the effect of photobiostimulation and pulsed electromagnetic field in patients with chronic rhinosinusitis on: * Quality of life. * Pulmonary function. * Mean platelet volume. * headache . * total nasal symptoms.
Detailed description
Chronic rhinosinusitis is a severe disease that significantly impacts a patient's quality of life, leading to significant economic impacts on healthcare resources and absenteeism. Symptoms interfere with daily activities and can lead to medication resistance. Treatment options like steroids, oral antibiotics, and sinus surgery are less effective, and disease recurrence remains high even after surgery. Alternative therapies like low-level laser therapy and pulsed electromagnetic filed have shown promise in improving symptoms and potentially making low-level laser therapy a non-invasive treatment for Chronic rhinosinusitis
Interventions
We will use the ASTAR Physio MG 827, a generator and 75 cm solenoid couch, in a pulsed electromagnetic field group. Participants will be placed comfortably in the solenoid, and the device will be turned on and programmed for 20 guesses for 10 minutes, 7 Hz, three times per week for 8 weeks.
DEVICEPhotobiostimulation
The therapy will be performed using an ASTAR PhysioGo -As low level laser therapy device with a wavelength of 830 nm, 30 mW power output, and 1 J energy dose. Patients will be supine and wear laser safety goggles. The laser will be applied to six locations over the maxillary or frontal sinuses, administered in a continuous manner for 33 seconds per spot, totaling 198 seconds and 6 J per session
OTHERSelf-sinus massage technique
Participants are instructed to perform self-massage to their frontal and maxillary sinuses at home twice daily, in the morning and evening. For the frontal sinus, place the fingers above the eyebrows on either side of the forehead, and gently circular outward massage for three sets of 30 seconds, repeated twice a day.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
1. Participants suffering from mild to moderate symptoms (baseline Total nasal symptoms score ≤ 9). 2. Subjects age range from 20 to 40 years old. 3. Patients of both sexes. 4. proven positive allergy test (skin prick test or multiple allergen simultaneous test) to any of the common perennial allergens such as dust mites, molds, insects, and animal dander within the last 12 months
Exclusion criteria
* Pregnant or breastfeeding women. * Patients with a definite deviated nasal septum, or history of operation within the last 6 months. * Hypertension, diabetes mellitus, malignancy, active pulmonary tuberculosis, active respiratory disease like asthma, or other systemic diseases. * Long-term use of corticosteroids or immunosuppressive agents. * Participation in another clinical study within 30 days. * Hyperthyroidism * Patients who had used antihistamines within 1 week, topical corticosteroids within 2 weeks, systemic corticosteroids within 4 weeks, anticholinergic drugs within 3 days, antileukotriene drugs within 1 week, decongestants within 3 days, tricyclic antidepressants or phenothiazines within 2 weeks, nonsteroidal analgesics within 2 weeks, and other drugs that the researchers believed were inappropriate. * Patients with Tattoos, moles and dark skin
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| assessment of change of quality of life | at baseline and after 8 weeks | The Sinonasal Outcome Test-22 questionnaire is a commonly used tool in clinical practice to assess patients' quality of life with chronic respiratory syndrome. It consists of 22 chronic respiratory syndrome-related items, ranging from 0 to 5, and categorizes them into physical symptoms (items 1-12) and health and quality of life (items 13-22), covering sleep function and psychological difficulties. It is easy to understand and complete. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| assessment of change of pulmonary functions | at baseline and after 8 weeks | The Global Initiative for Chronic Obstructive Lung Disease 2010 guidelines outline a procedure for a spirometer. The patient is instructed to breathe in until their lungs feel full, then hold their breath tightly around the mouthpiece. The operator blasts the air out forcefully, encouraging the patient to continue. The procedure is repeated twice until three repeatable blows are obtained, with the best two readings within 150 mL or 5% of each other. |
| assessment of change of Mean platelet volume | at baseline and after 8 weeks | Venous blood samples will be drawn to assess and calculate the average volume of individual platelets |
| assessment of change of white blood cells count | at baseline and after 8 weeks | Venous blood samples will be drawn to assess and calculate the white blood cells count |
| assessment of change of headache pain severity | at baseline and after 8 weeks | It will be used to evaluate headache pain severity using a standard horizontal scale as mild (1-3 on a visual analogue scale), moderate (4-6 on a visual analogue scale), severe (7-9 on a visual analogue scale) and very severe (10 on a visual analogue scale) |
| assessment of change of total nasal symptoms | at baseline and after 8 weeks | It is the sum of scores for nasal congestion, sneezing, nasal itching, and rhinorrhea at each time point, using a four-point scale (0-3). A score of 0 indicates no symptoms, a score of 1 indicates mild symptoms that are easily tolerated, a score of 2 indicates awareness of bothersome but tolerable symptoms, and a score of 3 indicates severe symptoms that interfere with daily activities. The total nasal symptoms scale is calculated by combining the scores for each symptom to a total of 12 |
Countries
Egypt
Contacts
Primary ContactSamar Said Abd AL-razek, physical therapist
Outcome results
None listed