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Evaluation of Decision Compatibility Between a Multidisciplinary Cancer Board and ChatGPT-4O

Agreement Between Multidisciplinary Cancer Board Decisions and ChatGPT-4O in Clinical Decision-Making: A Cross-Sectional Observational Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06986564
Enrollment
100
Registered
2025-05-23
Start date
2024-11-01
Completion date
2025-05-01
Last updated
2025-05-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Artificial Intelligence, Cancer

Keywords

Clinical decision agreement study, Cancer, Artificial intelligence

Brief summary

This study aims to compare the decisions of a multidisciplinary cancer board at Van research and educational Hospital with those generated by ChatGPT-4O. Patient data, including age, gender, comorbidities, clinical findings, laboratory results, radiology, and pathology reports, will be collected and recorded in patient files. These records will then be converted into a textual format appropriate for input into the ChatGPT-4O model. Statistical analyses will be conducted to assess the level of agreement between the board's decisions and those of ChatGPT-4O, providing insights into their compatibility and potential utility in clinical practice.

Detailed description

This study aims to evaluate the agreement between decisions made by a multidisciplinary cancer board at Van Hospital and those generated by the ChatGPT-4O model. A total of 100 cancer patients presented to the multidisciplinary cancer board will be included in the study. Patient data, including age, gender, comorbidities, clinical findings, laboratory results, radiology, and pathology reports, will be systematically recorded and reformatted into text suitable for the ChatGPT-4O model. The AI model's decisions will then be compared to those made by the cancer board. Statistical analyses will be performed to quantify the level of agreement between the two decision sources. The findings will provide insights into the compatibility between human-led multidisciplinary decisions and AI-driven recommendations, highlighting areas of agreement and disagreement. This study will assess the potential utility of ChatGPT-4O in clinical oncology decision-making and explore whether AI models can support or complement traditional cancer board processes.

Interventions

None listed

Sponsors

Sebahattin Celik MD
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* above 18 y/o * patients diagnosed with malignancy

Exclusion criteria

* patients who refused to consent

Design outcomes

Primary

MeasureTime frameDescription
to evaluate the agreement between decisions made by a multidisciplinary cancer board and those generated by the ChatGPT-4O model using kappa statistics.4 monthWithin the scope of this research, we aimed to elucidate the compatibility of artificial intelligence with the decisions made in patients brought to the multidisciplinary tumor council. We sought to answer whether we can accept artificial intelligence as a new member, other than humans, as a decision-support tool in the council.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026