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Predictive Ability of Different Frailty Indices for Postoperative Infections in Elderly Patients

Evaluating the Predictive Ability of Different Frailty Indices for Postoperative Infections in Elderly Patients: Data Analysis From a Prospective Multicenter Observational Cohort

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06985771
Enrollment
10536
Registered
2025-05-22
Start date
2025-03-01
Completion date
2025-05-06
Last updated
2025-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Frailty, Postoperative Infections

Keywords

Frailty, Postoperative Infection, elderly patients

Brief summary

In this study, we extracted data from the patients medical record within the cohort to compare five existing frailty indices: the 5-Item Modified Frailty Index (mFI-5), the Electronic Frailty Index (eFI), the Frailty Index based on Comprehensive Geriatric Assessment (FI-CGA), the Frailty Risk Assessment Instrument for the Elderly based on Laboratory and Clinical Indicators (FRAIL), and the Hospital Frailty Risk Score (HFRS). The study aims to evaluate the predictive values of each electronic frailty index for the incidence of postoperative infection-related adverse events. This includes the primary outcome of infection events occurring within 30 days and the secondary outcome of the correlations among the five frailty indices.

Interventions

OTHERObservational study, with no intervention.

Observational study, with no intervention.

Sponsors

The First Medical Center of Chinese PLA General Hospital
CollaboratorOTHER
Chinese PLA General Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. Aged 65 and above 2. Patients who underwent Non-Cardiac surgeries and anesthesia

Exclusion criteria

1. Patients who underwent surgery within 30 days before the current procedure; 2. Patients with missing baseline demographic data; 3. Patients with incomplete medical records that resulted in the inability to fully assess all five frailty indices; 4. Patients with missing data related to primary and secondary outcomes after surgery.

Design outcomes

Primary

MeasureTime frame
Postoperative infection events within 30 days postoperativelyWithin 30 days postoperatively

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026