The Effect of Preoperative Intravenous Fluid Bolus on Post-induction Hypotension in Elective Cystoscopies.

Status

Enrolling by invitation

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06985654

Enrollment

100

Registered

2025-05-22

Start date

2025-07-14

Completion date

2026-12-31

Last updated

2025-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postinduction Hypotension, Hypotension During Surgery

Keywords

postinduction hypotension, hypotension, cystoscopy, lactated ringers

Brief summary

This study aims to determine whether a standardized, weight-based crystalloid fluid bolus administered preoperatively reduces the incidence of postinduction hypotension (PIH) in patients undergoing cystoscopy.

Interventions

DRUGLactated Ringers

A bolus of Lactated Ringers (15mL/kg of ideal body weight) will be given to patients prior to anesthesia induction.

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Age ≥ 18 years old. 2. Undergoing elective cystoscopy surgery as the primary procedure. 3. Able to provide informed consent.

Exclusion criteria

1. Emergency surgeries. 2. Past history of amputations of any body part. 3. Allergies or contraindications to any medications used in the protocol or lactated ringers. 4. Systolic heart failure with LVEF \< 30% within the last year. 5. Severely depressed RV function within the last year. 6. Restrictive diastolic dysfunction within the last year. 7. Currently pregnant.

Design outcomes

Primary

Measure	Time frame	Description
Incidence of Postinduction Hypotension	From the time patient enters the operating room to the end of surgery, assessed up to 24 hours.	Number of patients that experience a decrease in mean arterial pressure (MAP) greater than 20% from the baseline MAP.

Other

Measure	Time frame	Description
Inferior Vena Cava Size	From the time of consent to the beginning of surgery, assessed up to 24 hours.	Size of the inferior vena cava before surgery, approximated using a point-of-care ultrasound scan
Respiratory Variability	From the time of consent to the beginning of surgery, assessed up to 24 hours.	Change in the size of the inferior vena cava during respiration, approximated using a point-of-care ultrasound scan

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026