Azoospermia, Nonobstructive, Male Infertility
Conditions
Brief summary
this study predicts the factors of successful micro testicular sperm extraction in azoospermia patients in male infertility
Detailed description
primary outcomes: these factors were the age, testicular size, hormonal, evidence of varicocles and the out come of Micro\_TESE secondary outcomes: make good decision for Micro-TESE with low economic laboratory and radiology requirement As every failed microTESE-ICSI procedure exposes the couple to an emotional, financial burden and increase the incidence of complication such as bleeding, hematoma and testicular atrophy
Interventions
PROCEDUREmicro-dissection testicular sperm extraction
dissection of the seminefrous tubules under microscope to extract sperms
Sponsors
South Valley University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
MALE
Healthy volunteers
Yes
Inclusion criteria
Non obstructive Azoospermia with no genetic abnormalties as klinefelter syndrome * redo Micro TESE
Exclusion criteria
* obstructive Azoospermia and bilateral congenital absent of vas
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sperm Retrieval Success Rate and identification of Predictive Factors | 1st 1 year | Determine which preoperative factors are significantly associated with successful sperm retrieval. These may include: Serum Follicle-Stimulating Hormone (FSH) Levels: Elevated FSH levels have been linked to reduced sperm retrieval success. And patient Age and testicular size to reach the best one to predict the success rate |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Assess the success rates of ART procedures following sperm retrieval and complications | 2 years | Assisted Reproductive Technology (ART) Outcomes Fertilization Rates: The percentage of oocytes successfully fertilized. Embryo Development: Quality and progression of embryos to the blastocyst stage. Clinical Pregnancy Rates: Confirmed pregnancies via ultrasound. Live Birth Rates: The ultimate success metric of ART procedures Complication Rates Monitor and document any complications arising from the sperm retrieval procedure, such as: Testicular Hematoma Infection Testicular Atrophy |
Countries
Egypt
Outcome results
None listed