Anterior Cruciate Ligament Injury, Knee Injury, Ligament Reconstruction, Sports Injuries
Conditions
Keywords
ACL reconstruction, Quadriceps tendon graft, Semitendinosus graft, DKRR, Knee ligament injury, Orthopaedic surgery, Registry study
Brief summary
This study looks at two different types of tendon (tissue) used in knee surgery to repair a torn anterior cruciate ligament (ACL), which is a common injury in active people. The two types are taken from different muscles in the thigh: one from the front (quadriceps) and one from the back (semitendinosus). We will use information already collected in a national health registry to see how patients recover after surgery. The study will compare knee function, activity level, and how often patients need another operation.
Detailed description
This is a retrospective observational cohort study based on data from the Danish Knee Ligament Reconstruction Registry (DKRR). The study includes patients who underwent primary ACL reconstruction using either a quadriceps tendon graft (with or without a bone block) or a quadrupled semitendinosus tendon graft. The primary outcome measures are the Knee Injury and Osteoarthritis Outcome Score (KOOS) and the Tegner Activity Scale. Secondary outcomes include reoperation rates, postoperative complications, and patient satisfaction. All available demographic, operative, and patient-reported outcome data will be analyzed. Multivariable regression will be used to adjust for confounders such as age, sex, BMI, time from injury to surgery, and surgeon volume. The study is exempt from ethical approval under Danish law, and data will be handled in compliance with GDPR.
Interventions
None listed
Sponsors
Søernes Privathospital
Abdirahman Hassan Omar
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
15 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Primary ACL reconstruction registered in the Danish Knee Ligament Reconstruction Registry (DKRR) * Known graft type: quadriceps tendon or semitendinosus tendon Minimum 1-year follow-up with completed patient-reported outcome measures (KOOS and/or Tegner score) * Age between 15 and 50 years at the time of surgery (optional subgroup analysis)
Exclusion criteria
* Revision ACL reconstruction * Multiligament knee reconstruction * Missing or incomplete PROMs or key clinical data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The Knee Injury and Osteoarthritis Outcome Score (KOOS) | At minimum 1 year follow up postoperatively | The Knee Injury and Osteoarthritis Outcome Score (KOOS) evaluates pain, symptoms, daily living, sport/recreation, and knee-related quality of life. Metric type: continuous PROM-based subscale score Method of measurement: Self reported questionnaire |
| Tegner Activity Score | Minimum 1 year follow up postoperatively. | Assesses patients' level of physical activity before injury and at follow-up. Metric type: Scale from 0-10, where 0 is no physical activity caused by knee problems and 10 is an ability to compete in elite level sport like soccer and ski. Method of measurement: Tegner scale, self reported |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Re-operation rate | Within 1 year of surgery | Incidence of surgical re-intervention after primary ACL reconstruction. Method of measurement: Registry recorded re-operations in DKRR |
| Postoperative complications | Within 1 year after surgery | Frequency of postoperative complications such as infection, stiffness, or graft failure. Metric type: Occurrence of postoperative complications Method of measurement: Clinically reported and registry documented complications in DKRR |
| Patient satisfaction | 1 year follow up | Overall patient satisfaction with surgical outcome, if available in registry. Metric type: PROM's available from the DKRR Method of measurement: Patient reported satisfaction score. |
Countries
Denmark
Contacts
Primary ContactAbdirahman Omar H Medical Students
Backup ContactMikkel Attrup L MD, Orthopedic Surgeon
Outcome results
None listed