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Comparison of a Face Cream Plus a Laser Procedure and Face Cream Alone in Treatment of Excessive Face Hairs in Female

Comparison of Eflornithine Cream Combined With Intense Pulsed Light Versus Intense Pulsed Light Alone for Hirsutism in Women

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06976424
Enrollment
122
Registered
2025-05-16
Start date
2025-07-15
Completion date
2025-12-31
Last updated
2025-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hirsuitism

Keywords

Hirsuitism, IPL, Eflornithine

Brief summary

The study compares the effects of a cream alone and a combined effect of cream and laser for the treatment of excessive facial hairs in women .

Detailed description

Hirsuitism refers to excessive terminal hairs in females, following a distribution pattern typically associated with male. It is associated with either increase response of hair follicles to androgen or either increase level of circulating androgens.The treatment options available are topical creams like eflornithine and laser treatments for hair removal. This study aims to conduct the comparison of a eflornithine cream and intense pulsed light laser versus eflornithine cream alone for the treatment of excessive facial hairs.

Interventions

Eflornithine cream will be applied to the face of group B female patients

RADIATIONInstense pulsed light

Intense pulse light will be applied to the face of patient of Group A on areas having increase hair. Patient will be called for a followup every month for next session.

Sponsors

Khyber Teaching Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

Gender (Female) Age between 18-45 Years Women with hirsutism as mentioned in the operational definition

Exclusion criteria

Pregnant women Women with severe acne Women with immunodeficiency

Design outcomes

Primary

MeasureTime frameDescription
Efficacy of treatment3 monthsEfficacy of treatment is defined as complete clearance of excessive hairs assesed on the basis of 4- level scale ranging 0 to 3 after 3 months of administration of the treatment in both groups. Clear is grade 3 Marked improvement is grade2 Improved is grade1 No improvement is grade 0

Countries

Pakistan

Contacts

Primary ContactUmaima Nazar, MBBS
umaimanazar123@gmail.com+923355869079

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026