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ASSOCIATION BETWEEN TEMPOROMANDIBULAR DISORDERS AND SLEEP DISORDERS

ASSOCIATION BETWEEN TEMPOROMANDIBULAR DISORDERS AND SLEEP DISORDERS

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06975709
Acronym
Gnathology TMD
Enrollment
100
Registered
2025-05-16
Start date
2025-04-01
Completion date
2026-04-01
Last updated
2025-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep, Temporomandibular Disorders (TMD)

Brief summary

ASSOCIATION BETWEEN TEMPOROMANDIBULAR DISORDERS AND SLEEP DISORDERS

Detailed description

Temporomandibular disorders (TMD) are complex conditions, which can have a significant impact on patients' health and quality of life. Furthermore, they are unclearly associated with sleep disorders. The aim of the study is to investigate the prevalence of TMD in patients with sleep disorders.

Interventions

OTHERQuestionnaire and Physical Exam

The diagnostic questionnaires will be administered and the participants' responses will subsequently be analyzed, evaluating the presence of temporomandibular disorders (DTMs) in patients with sleep disorders. The questionnaires will be administered to patients with a previous diagnosis of sleep disorder carried out at a specialist centre, consecutively belonging to the outpatient clinics of both centers U.O of Neurology-Sleep Disorders Center and U.O of Dentistry.

Sponsors

IRCCS San Raffaele
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age \>18 years * Famale and Male * Signature of the privacy information form * Signature of the informed consent form of the protocol * Subjects capable of understanding and wanting * Subjects suffering from a sleep disorder (Insomnia,Hypersomnia,Restless legs syndrome,REM sleep behavior disorder,Narcolepsy,Obstructive sleep apnea syndrome (OSAS),Primary snoring, REM parasomnias,Nocturnal epilepsy)

Exclusion criteria

* Physical trauma to the head and neck area * Painful oral pathologies (e.g. pulpitis, tooth fractures, tooth abscesses, tooth decay, canker sores and mucosal wounds) * Recent dental treatments that may cause pain (e.g. tooth extraction, tooth root canal) * Use of oral contraceptives * Subjects not capable of understanding and wanting * Patients suffering from neurological pathologies that may interfere with the completion of the questionnaires (ES dementia) or psychiatric pathologies or drug use as per DSM-5 criteria (including schizophrenia, bipolar, major depression, substance abuse, personality disorders).

Design outcomes

Primary

MeasureTime frameDescription
Primary Outcomeat enrollmentThe main aim of the present study is to evaluate the prevalence of TMDs in patients with sleep disorders. This population was selected in order to contribute, in the context of scientific research, to the investigation into the association between temporomandibular disorders and sleep disorders, which include all those disorders that compromise both the quantity and quality of sleep with repercussions important on general health and quality of life, like: * Insomnia * Hypersomnia * Restless legs syndrome * REM sleep behavior disorder * Narcolepsy * Obstructive sleep apnea syndrome (OSAS) * Primary snoring * REM parasomnias (Sleepwalking, arousal disorders, excessive daytime sleepiness and night terrors) * Nocturnal epilepsy Patients with sleep disorders may be recruited in the observational study conducted by the University's Department of Dentistry Vita-Salute San Raffaele and the Neurology-sleep disorders unit of the San Raffaele Hospital in Turro, aimed at evaluating the prevalence of T

Secondary

MeasureTime frameDescription
Secondary Outcomeat enrollmentThrough this study we also want to evaluate the difference between the prevalence of TMDs in patients with sleep disorders and the prevalence of TMDs in non-patological population through the data present in the scientific literature.

Countries

Italy

Contacts

Primary ContactSimona Tecco, MD
tecco.simona@hsr.it+390226432970
Backup ContactLuigi Ferini-Strambi, MD
ferinistrambi.luigi@hsr.it+390226433363

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026