Iron Biomarkers/Status
Conditions
Keywords
vertical farming, iron biomarkers, iron status, biofortification, microgreens
Brief summary
The investigators present a pilot diet intervention study, to be conducted as a within-subject design, to assess the feasibility of iron biofortified microgreens on iron intake and status in women of reproductive age and postmenopausal women. This will be investigated by providing smoothie kits for 28 days containing these microgreens and determining the impact on iron biomarkers. The investigators will also assess habitual diet, BMI, physical activity and gastrointestinal symptoms. This study will be a proof-of-concept exploratory study to explore diet based biofortification through vertical farming systems.
Detailed description
In this study microgreens that were grown using agronomic iron biofortification will be supplied to women to add to their diet to establish the potential nutritional impact of iron biofortified microgreens on overall iron intake and iron status. Furthermore, it will assess the adherence to the provided consumption recommendations of the biofortified crops.
Interventions
OTHERSmoothie containing iron biofortified microgreens
30g of iron biofortified microgreens consumed within a smoothie for 28 days
Sponsors
University of Aberdeen
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Healthy females * 15 of reproductive age (18-49) * 15 postmenopausal (not had their period for an entire year)
Exclusion criteria
Medication
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Haemoglobin status change from baseline | Measured at study day 1 and on study day 28 | Iron status changes in haemoglobin |
| Dietary iron intake changes compared to habitual diet | every study day (28 days) | Dietary iron intake changes in iron intake compared to habitual diet measured though food diaries |
| Ferritin status change from baseline | Measured at study day 1 and on study day 28 | Iron status changes in ferritin |
| CRP change from baseline | Measured at study day 1 and on study day 28 | Changes in CRP |
| Serum iron status change from baseline | Measured at study day 1 and on study day 28 | Iron status changes in serum iron |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Serum Vitamin B12 status change from baseline | Measured on study day 1 and on study day 28 | Vitamin B12 status changes |
| Adherence to consumption of microgreens/smoothie | every study day (28 days) | intake measured through food diaries |
Countries
United Kingdom
Contacts
PRINCIPAL_INVESTIGATORAlexandra Johnstone, Prof
University of Aberdeen, Rowett Institute of Nutrition and Health
Outcome results
None listed