TEMPS-A and Menopause Symptoms

The Relationship Between Temperament and Menopause Symptoms: A Cross-Sectional Study Using TEMPS-A and MRS Scales

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06972290

Acronym

TEMPS-MRS

Enrollment

105

Registered

2025-05-15

Start date

2024-01-01

Completion date

2025-05-30

Last updated

2025-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menopause, Personality, Temperament

Keywords

Menopausal Transition, Personality Traits, Personality Characteristics

Brief summary

This study investigates the relationship between temperament traits and menopausal symptoms using the TEMPS-A and MRS scales in women at menopausal transition stages. It is a cross-sectional observational study.

Detailed description

This observational, cross-sectional study aims to investigate the relationship between temperament traits and menopausal symptoms in women in the menopausal transition stage, specifically classified as STRAW stages -1, +1a, and +1b. Participants are recruited from menopause outpatient clinics. Data are collected through the administration of the validated Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire (TEMPS-A) and the Menopause Rating Scale (MRS). Participants voluntarily complete the questionnaires after providing informed consent. All responses are anonymized and securely stored. Quality assurance measures include verification of data entry, use of validated scales, and compliance with ethical standards approved by the Istanbul Medipol University Non-Interventional Clinical Research Ethics Committee. No interventions are applied; the study strictly follows observational registry procedures.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

No minimum to 55 Years

Healthy volunteers

Yes

Inclusion criteria

* Women classified as STRAW stages -1, +1a, and +1b (menopausal transition stages) * Ability to complete questionnaires and provide informed consent

Exclusion criteria

* History of hormone therapy during the past 6 months * History of surgical menopause (bilateral oophorectomy) * Presence of severe physical disorders (e.g., malignancy, severe cardiovascular diseases) * Presence of severe psychological disorders (e.g., major depressive disorder, psychosis)

Design outcomes

Primary

Measure	Time frame	Description
MRS Total Score at Baseline	Baseline (single time point at enrollment)	Total score from the Menopause Rating Scale (MRS), reflecting overall menopausal symptom severity.
TEMPS-A Depressive Subscale Score at Baseline	Baseline (single time point at enrollment)	Score from the depressive subscale of the TEMPS-A questionnaire, assessing baseline depressive temperament
TEMPS-A Cyclothymic Subscale Score at Baseline	Baseline (single time point at enrollment)	Score from the cyclothymic subscale of the TEMPS-A questionnaire, assessing mood instability.
TEMPS-A Hyperthymic Subscale Score at Baseline	Baseline (single time point at enrollment)	Score from the hyperthymic subscale of the TEMPS-A questionnaire, assessing elevated or overly positive mood tendencies.
TEMPS-A Irritable Subscale Score at Baseline	Baseline (single time point at enrollment)	Score from the irritable subscale of the TEMPS-A questionnaire, assessing baseline tendency toward irritability.
TEMPS-A Anxious Subscale Score at Baseline	Baseline (single time point at enrollment)	Score from the anxious subscale of the TEMPS-A questionnaire, assessing trait anxiety.
MRS Somatic Subscale Score at Baseline	Baseline (single time point at enrollment)	Somatic subscore of the MRS, measuring physical symptoms such as hot flashes and sleep problems.
MRS Psychological Subscale Score at Baseline	Baseline (single time point at enrollment)	Psychological subscore of the MRS, reflecting symptoms such as depressive mood, irritability, and anxiety.
MRS Urogenital Subscale Score at Baseline	Baseline (single time point at enrollment)	Urogenital subscore of the MRS, assessing symptoms such as vaginal dryness or urinary complaints.

Secondary

Measure	Time frame	Description
Correlation Between TEMPS-A Subscale Scores and MRS Total/Subscale Scores	Baseline (single time point at enrollment)	The relationship between affective temperament traits (TEMPS-A: depressive, cyclothymic, hyperthymic, irritable, and anxious) and menopausal symptom severity (MRS total and subscale scores) will be assessed using Pearson or Spearman correlation coefficients. The analysis aims to determine whether specific temperament profiles are associated with increased symptom burden.

Countries

Turkey (Türkiye)

Outcome results