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Analysis of Recurrence of Intraductal Papilloma Treated With Vacuum-assisted Rotary Excision

Analysis of Factors Associated With Postoperative Recurrence of Intraductal Papilloma of the Breast Treated With Ultrasound-guided Vacuum-assisted Rotary Excision

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06970561
Acronym
IDP
Enrollment
106
Registered
2025-05-14
Start date
2020-01-06
Completion date
2024-09-01
Last updated
2025-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign Breast Tumors, Breast Cancer Surgery

Keywords

intraductal papilloma of the breast, treatment, vacuum-assisted rotational excision therapy

Brief summary

To study the postoperative recurrence of intraductal papillomas (IDP) treated with ultrasound-guided vacuum-assisted excision (VAE), and to investigate the effect of different lesion characteristics on recurrence.

Detailed description

106 patients with IDP with or without atypical ductal hyperplasia (ADH) treated with ultrasound-guided VAE at Zhongnan Hospital of Wuhan University from January 2020 to August 2024 were selected for the study, and the postoperative conditions of the patients were sorted out and followed up to analyze the characteristics of the lesions and to determine the relevant factors that affected the postoperative recurrence.

Interventions

PROCEDUREenlarged resection

patients underwent secondary enlarged resection within 1 month after the diagnosis of IDP combined with ADH,

Sponsors

Wuhan Children's Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Healthy volunteers
No

Inclusion criteria

* IDP was diagnosed pathologically after VAE treatment * the tumor was a solitary lesion with the margin \>1cm from the nipple and the longest diameter of the tumor \<3cm * it was not associated with other breast diseases

Exclusion criteria

* previous ductal breast surgery * abnormal coagulation function or taking anticoagulant drugs .recent or current use of hormonal or psychotropic drugs.

Design outcomes

Primary

MeasureTime frameDescription
recurrenceThe cut-off date for follow-up was September 2024Recurrence was defined as the appearance of a lesion within 2-3 cm of the original surgical area with corresponding clinical manifestations, such as nipple discharge and imaging support, which was later pathologically confirmed as IDP

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026