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Prognostic Value of Capillary Lactatemia in Potentially Severe Polytrauma Patients

Prognostic Value of Capillary Lactatemia in Potentially Severe Polytrauma in Pre-hospital Care

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06969404
Acronym
CLAT
Enrollment
550
Registered
2025-05-13
Start date
2026-02-07
Completion date
2027-12-15
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polytrauma

Brief summary

Nowadays, the tools available to assess the severity of a polytrauma patient in the pre-hospital setting (vital parameters, shock index, MGAP score, Vittel criteria) have their limitations and are sometimes subjective. To date, there are no objective, practical and reproducible tools for triaging these patients. Venous lactataemia also appears to be predictive of poor outcome in severe trauma. However, there are no studies in the literature on capillary lactataemia, which would indicate the potential severity of a polytrauma patient in the pre-hospital setting. However, it is an easily performed, risk-free assay, the results of which can be obtained rapidly at the scene of the accident. The aim of this project is to confirm that, like venous lactataemia, capillary lactataemia can be useful in the pre-hospital phase for predicting a patient's poor outcome. Incorporating this assay into the assessment of potentially severe polytrauma patients in the pre-hospital phase could improve the predictive value of clinical and contextual data and thus enable better referral and management of these patients.

Interventions

capillary blood sampling during the hospital transfert

Sponsors

Centre Hospitalier Universitaire de Nice
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patient over 18 years of age * Presenting a potentially serious pre-hospital trauma defined by: o A road accident or a fall of more than 2 metres * Requiring the dispatch of a SMUR 06 team (mobile emergency and resuscitation service) * And transferred to an emergency facility in the Alpes Maritimes with medical assistance. * Consent signed (by the patient or a relative) after the event if it is not possible to sign immediately. * Pregnant women may also take part in the study without any risk to themselves or their child.

Exclusion criteria

* Patients with isolated peripheral limb trauma (wrist, elbow, knee, ankle, shoulder) * Patients under legal protection (guardianship, curatorship) * Patients in cardiorespiratory arrest when taken into care by the SMUR (emergency medical services)

Design outcomes

Primary

MeasureTime frameDescription
lactemie value H0at inclusiondosage of capillary lactemia in mmol/L
lactemie value H66 hoursdosage of capillary lactemia in mmol/L

Countries

France

Contacts

CONTACTMarta FERNANDES FEIRRERA, PH
fernandes-feirrera.m@chu-nice.fr0629847289

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 31, 2026