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Research on the Real-World Community Application of Large Language Models

Research on the Real-World Community Application of Large Language Models

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06966882
Enrollment
314
Registered
2025-05-13
Start date
2025-05-31
Completion date
2026-12-31
Last updated
2025-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ophthalmic Diseases (Specific Types Not Restricted)

Brief summary

There is an imbalance between the supply and demand of eye care services, especially in local communities and remote areas. To address this, it's important to use new intelligent technologies to expand the reach of eye disease screening and treatment. Large language models (LLMs) are a type of deep learning technology that can learn from large amounts of text and generate human-like language to help with medical tasks such as diagnosing diseases and answering health-related questions. The investigator's team has previously developed a localized LLM capable of answering ophthalmology-related medical questions. Building on this, this study plans to use a screening-based trial design to explore how accurately the LLM can make referral decisions for eye diseases, diagnose conditions, recommend appropriate tests, and receive user feedback in real-world community settings. The goal is to improve the ability to screen for eye diseases in grassroots and regional areas.

Interventions

None listed

Sponsors

Zhongshan Ophthalmic Center, Sun Yat-sen University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* Participants of any age and gender * Belonging to one of the following ophthalmic categories: Patients requiring specialist referral;Patients manageable at community level;Individuals without ocular pathology * Voluntary participation with written informed consent

Exclusion criteria

* Investigator-determined clinical contraindications

Design outcomes

Primary

MeasureTime frame
Metrics for Evaluating Referral Accuracy of Large Language Models: Sensitivity, Specificity, Accuracy, Positive Predictive Value, Negative Predictive Value.through study completion, up to 1 year.

Contacts

Primary ContactHaotian Lin
haot.lin@hotmail.com86-13802793086
Backup ContactMingjie Luo
zoc_mjluo@yeah.net86-18200202414

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026