Computational Cardiac Imaging Analysis to Guide Ventricular Tachycardia Ablation Procedures (AI-VT)

Prospective Use of Computational Cardiac Imaging Analysis to Guide Ventricular Tachycardia Ablation Procedures (AI-VT)

Status

Enrolling by invitation

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06964152

Acronym

AI-VT

Enrollment

250

Registered

2025-05-09

Start date

2024-05-01

Completion date

2034-12-31

Last updated

2025-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premature Ventricular Contraction (PVC), Ventricular Fibrillation, Ventricular Tachycardia (VT)

Keywords

electrocardiography, arrhythmia mapping, 3D mapping, electroanatomic mapping, cardiac computed tomography, artificial intelligence, computational modeling

Brief summary

The purpose of this study is to evaluate the clinical outcomes (clinical efficacy and safety) of using supplemental non-invasive computational ECG and cardiac imaging analysis tools to help guide ablation of ventricular tachycardia.

Interventions

DIAGNOSTIC_TESTComputational electrocardiography and cardiac computed tomography mapping

Use of non-invasive computational ECG and cardiac CT models to localize arrhythmia origins

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

21 Years to 90 Years

Healthy volunteers

Inclusion criteria

1. Age between 21 and 100 2. Evidence of ventricular tachycardia on ECG, telemetry or by CIED interrogation.

Design outcomes

Primary

Measure	Time frame	Description
Recurrent ventricular tachycardia	1 year	Ventricular tachycardia episodes defined as implantable cardioverter defibrillator (ICD) therapies (anti-tachycardia pacing and shocks)
All-cause death	1 year	—

Secondary

Measure	Time frame	Description
acute cerebrovascular accident (embolic)	24 hours post-op	—
Acute hemodynamic decompensation	24 hours post-op	acute development of hypotension, cardiogenic shock, escalation of inotropes/pressors, or need for unplanned percutaneous hemodynamic support
vascular complication requiring intervention	24 hours post-op	vascular access complication (bleeding or occlusion) requiring blood transfusion or vascular procedure (such as peripheral angioplasty)
acute pericardial tamponade requiring intervention	24 hours post-op	new expanding hemorrhagic pericardial effusion causing tamponade requiring urgent pericardiocentesis
Unplanned prolonged ICU upgrade	48 hours	In outpatient elective cases, change in patient condiction neccessitating unplanned ICU upgrade lasting longer than 48 hours.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026