Osteoarthritis (OA) of the Knee
Conditions
Brief summary
Degenerative and traumatic diseases of the musculoskeletal system lead to increased immobility of a patient, which in turn results in muscle atrophy. BFR training is a training method in which a blood pressure cuff partially blocks the arterial blood flow to the exercising limb and completely blocks the venous blood flow. During exercise, an externally induced venous occlusion occurs. This stimulus increases the metabolic stimulus in the occluded extremity - this means that strength can be increased even with low weights, which is why this training is also suitable for people who should not use high training loads due to injuries or operations.
Interventions
OTHERSham-BFR
Six-week prehabilitation program (2/week): Unilateral Leg Press and Leg extension exercise with 30% of the individual 1RM by using a sham-BFR intervention with 20mmHg exercise pressure.
OTHERBFR
Six-week prehabilitation program (2/week): Unilateral Leg Press and Leg extension exercise with 30% of the individual 1RM by using a BFR intervention with an exercise pressure corresponding to 60% of the individual LOP.
Sponsors
University Hospital, Bonn
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Indication for TKA Surgery * Ability to perform prehabilitation exercise
Exclusion criteria
* Sickle Cell Anemia * Iatrogenic changes in the vessels of the lower extremities (e.g. stents) * Open wounds/Infection of the lower extremities
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Subjective Pain Value | Pre- to 6 weeks Post Surgery | Subjective pain perception, assessed by visual analog scale (0-100mm) |
| Muscle Strength | Pre- to 6 weeks Post Surgery | Muscle Strength assessed by isometric maximal test (Nm) |
Countries
Germany
Outcome results
None listed