Skip to content

Acute Effect of Isometric Excercise on Pain Sensitivity in Adults With Chronic Low Back Pain

Acute Effect of Isometric Excercise on Pain Sensitivity in Adults With Chronic Low Back Pain

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06963658
Enrollment
90
Registered
2025-05-09
Start date
2025-08-01
Completion date
2026-01-01
Last updated
2025-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Low Back Pain (CLBP)

Keywords

pain sensitivity, isometric exercise, low back pain

Brief summary

Randomized control trial to examine the immediate effect of isometric exercise on pressure pain threshold (PPT) in adults with chronic low back pain. The secondary aim of this study was to investigate the acute effects of isometric exercise on clinical pain intensity.

Detailed description

Participants will attend a single visit to the hospital for two hours, which will include collecting demographic details and clinical characteristics through self-reported assessment scales. After that, outcome measures (pain sensitivity and current low back pain intensity) were collected prior to the intervention and repeated immediately post-intervention.

Interventions

OTHERMultiple repetition isometric wall squat

Participants were directed to rest their backs against the wall with shoulder width apart and feet parallel, then descend until they achieve an angle of 100 degrees at knee joint. The knee joint angle was assessed using a goniometer placed on the lateral epicondyle of the knee, aligned with the femur, while the anchor arm was aligned with the lateral malleolus. They were instructed to maintain the isometric hold for up to three minutes, or until volitional fatigue was reached.with a 30-second rest period between each squat hold.

OTHERMultiple Isometric wall squat exercise + Double Leg Lower with Isometric Hold

Participants were directed to rest their backs against the wall with shoulder width apart and feet parallel, then descend until they achieve an angle of 100 degrees at knee joint. The knee joint angle was assessed using a goniometer placed on the lateral epicondyle of the knee, aligned with the femur, while the anchor arm was aligned with the lateral malleolus. They were instructed to maintain the isometric hold for up to three minutes, or until volitional fatigue was reached.with a 30-second rest period between each squat hold. Immediately post 60 second rest, Determine the participant's maximum angle using the double leg lowering test from supine position let the participant with both legs straightened before lifting the posterior hip, lowering the legs to a specific angle. Turn on the stopwatch. Hold the position near--maximally, try to achieve on (IES=9/10) and hold for the longest duration. They should reach 4 minutes for 3 repetition with 30 seconds rest between repetition

OTHERControl quiet seated rest

The control group served as the control group and did not perform any exercise. Participants were instructed to sit quietly in a standard height stationary clinical room patient chair for the entire eight minutes.

Sponsors

Taif University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

: 1. participants aged ≥18 years or older 2. participant diagnosed with non-specific chronic lower back pain (\> 12 weeks) 3. Able to perform physical therapy excercise .

Exclusion criteria

: The study will exclude 1- pregnant women 2- lactating women for one or less than one year post-natal. 3- any certain medical conditions that could interfere with physical activity, including: * uncontrolled diabetes * cardiovascular problem * orthopedic impairments * balance problems. 4-serious spinal pathologies : * infection * fractures * tumors * inflammatory diseases like ankylosing spondylitis 5- neurological compromise, * spinal nerve compromise * cauda equina syndrome

Design outcomes

Primary

MeasureTime frameDescription
The primary outcome is pain sensitivitypre- and immediately post-interventionPain sensitivity was assessed via pressure pain threshold (PPT) using a standard procedure. The PPT was assessed by a digital pressure algometer (Wagner digital force Ten FDX 25 with 1 cm 2 rubber tip).This instrument has been widely utilized in various studies and has been shown to be valid and reliable in assessing PPT among people with musculoskeletal pain. If post intervention PPT was higher than pre-intervention value, this indicated that pain sensitivity decreased, suggesting exercise induced hypoalgesia occurred. If post-intervention PPT was lower than pre-intervention PPT, this indicates that pain sensitivity increased, suggesting that exercise induced hyperalgesia occurred.

Secondary

MeasureTime frameDescription
The secondary outcome is the pain intensity in the lower backpre- and immediately post-interventionIt is a subjective rating of pain intensity in the lower back using a visual analog scale,where a rating of zero indicates that participant don't have pain and a rating of 10 indicates that the most severe pain. The VAS is reliable and valid for measuring pain in individuals with chronic musculoskeletal conditions. A change of one point in pain intensity on this scale is regarded as the minimal clinically important difference.

Countries

Saudi Arabia

Contacts

Primary ContactAsma A Alqahtani, B.S.C
Alqahtaniasma61@gmail.com966504435372
Backup ContactHosam A Alzahrani, PHD
halzahrani@tu.edu.sa966550668282

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026